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儿科病房产超广谱β-内酰胺酶菌的检测
引用本文:李瑞珍,马新瑜,何文军,刘先洲,唐芳,陈莎,罗德涓.儿科病房产超广谱β-内酰胺酶菌的检测[J].中国妇幼保健,2007,22(8):1064-1065.
作者姓名:李瑞珍  马新瑜  何文军  刘先洲  唐芳  陈莎  罗德涓
作者单位:1. 湖北省武汉市妇女儿童医疗保健中心内科,430016
2. 武汉大学医学院微生物教研室
摘    要:目的:调查儿科病房产超广谱β-内酰胺酶(extended-spectrum beta-lactam ases,ESBLs)菌的感染和耐药状况。方法:用纸片初筛试验和表型确证试验检测ESBLs,用K-B纸片扩散法对抗菌药物进行敏感试验。结果:大肠埃希菌和克雷伯菌是产ESBLs的两种主要革兰氏阴性杆菌。产ESBLs菌的耐药率与不产ESBLs菌相比差异有显著性。结论:儿科病房产ES-BLs菌所导致的感染已不容忽视;产ESBLs菌对大多数抗生素耐药。

关 键 词:超广谱β-内酰胺酶  耐药性  儿科
文章编号:1001-4411(2007)08-1064-02
修稿时间:2006年4月15日

Survey of bacteria producing extended -spectrum beta -lactamase in pediatrics
LI Rui-Zhen,MA Xin-Yu,HE Wen-Jun,et al..Survey of bacteria producing extended -spectrum beta -lactamase in pediatrics[J].Maternal and Child Health Care of China,2007,22(8):1064-1065.
Authors:LI Rui-Zhen  MA Xin-Yu  HE Wen-Jun  
Institution:LI Rui-Zhen,MA Xin-Yu,HE Wen-Jun,et al.Wuhan Women Children Medical Treatment Health Care Center,Wuhan 430016,Hubei,China
Abstract:Objective:To investigate the infection and drug resistance of extended-spectrum beta-lactamases(ESBLs)-producing bacteria in pediatrics.Methods:ESBLs were detected by two kinds of methods.The drug-sensitive test of ESBLs-producing strains was done according to K-B method.Results:Escherichia coli and Klebsiella were two main kinds of ESBLs-producing bacteria.There were significant differences between the resistance rates of ESBLs-producing strains and no ESBLs-producing strains.Conclusion:The infections of ESBLs-producing strains are serious in pediatrics.The resistant rates of ESBLs-producing strains to most antibiotics are high.
Keywords:ESBLs  Drug resistance  Pediatrics
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