泌尿生殖系统支原体检测及药敏分析

目的:了解本地区非淋菌性泌尿生殖系统支原体感染及药敏情况,为临床治疗提供依据,以提高疗效。方法:采用法国生物—梅里埃公司生产的支原体试剂盒对588例泌尿生殖道感染患者的泌尿生殖道标本进行支原体培养、鉴定及药敏分析。结果:588例泌尿道患者支原体培养阳性率为35.26％(206/588),其中解脲支原体(Uu)感染阳性率为27.85％(157/588),人型支原体(Mh)感染阳性率为3.35％(22/588),Uu-+Mh混合感染阳性率为4.06％(27/588),解脲支原体感染显著高于人型支原体及混合感染(P<0.01)。男女Uu感染阳性率分别为13.83％(30/286)和42.06％(127/302),有显著性差异(P<0.01),女性感染率明显高于男性。对8种抗生素的药敏试验结果为交沙霉素抑菌能力最强,以下依次为原始霉素、克拉霉素、强力霉素、美满霉素、阿奇霉素、罗红霉素、司帕霉素。结论:非淋菌性泌尿生殖道感染由支原体感染引起者呈逐渐上升趋势,其中以女性患者居多,临床治疗可根据药敏试验结果选择药物,以减少盲目性和耐药性。

Analysis of mycoplasma and drug sensitivities in urogenital tract infection

Objective: To study the drug sensitivities of mycoplasma in the patients of nongonococal urethritis. Methods: 588 specimens were collected from urogenital tract and were cultured and tested for drug sensitivities. Results: In 588 cases, there were 206 patients who had mycoplasma in the urogenital tract (35.26%). The simple infection of ureaplasma urealyticum (Uu) was 157 cases (27.85%), the simple mycoplasma hominis (Mh) was 22 cases (3.35%), the mixed was 27 cases (4.06%). The infection rate of Uu was higher than Uu Mh. The male was 13.83%(30/286), the female was 42.06%(127/302). The infection rate of female was higher than male. The results of drug sensitivities test showed that resistance of mycoplasma to Josamycin was highest, then they were Clarithromycin, Doxycycline, Minocin, Azithromycin, Roxithromycin, Spara in turn. Conclusion: Urogenital tract ingection caused by mycoplasma was increasing, especially in female. The patients were trated with antibiotics according to the drug sensitivities analysis.