窒息新生儿器官功能损害的临床分析

目的:了解窒息新生儿器官功能损害的发生率、程度及临床特点,探讨与之相关的高危因素。方法:将172例窒息新生儿按孕周、体重、窒息程度、宫内窘迫、体温多因素进行分组研究,并将各器官的功能损害分为轻度与重度加以分析。结果:窒息后器官损害发生率为85.5%,多器官损害发生率为58.7%。重度窒息组器官损害发生率及多器官损害发生率明显高于轻度窒息组(χ2=8.31,P<0.05)。窒息后器官损伤占首位的是大脑,其次为肾脏、心脏、电解质、胃肠、代谢、肺脏、肝脏。多器官损害随脏器损害个数的增加重度器官损害发生率逐渐升高,且死亡率亦升高。结论:器官损害发生率及程度与孕周、体重、窒息程度、低体温有相关性。提示应加强围产期保健,减少早产儿、低出生体重儿出生,注意保暖,减少冷损伤,提高医护人员复苏水平,可降低新生儿窒息、器官损害发生率及死亡率。

Clinical analysis of organic impairment in neonates with asphyxia

Objective:To evaluate the incidence and degree of organic impairment and clinical characteristic after neonatal asphyxia,analyze the high risk factors with the resultant injuries.Methods:One hurdred and seventy-two newborns with pregnant weeks,weight,degree of asphyxia,poverty-stricken in uterus,temperature were studied.And involved organs were classified as moderate or severe to analyze.Results:The incidence of organic impairment and multi-organ impairment with asphyxia were 85.5% and 58.5% respectively.The frequency of organ dysfunction neonate multiple organ impairment syndrome in severe asphyxia was significantil higher than that of mild group(P<0.05).Brain was the first,and others were kidney,heart,dielectric,gastroinestinal,metabolism,pulmonary,liver.The frequency of severe injuries and death were significantly higher with amounts of organic impairment.Conclusion:The incidence and degree of organic impairment were related to pregnant weeks,weight,asphyxia,lower temperature。It suggests that the perinatal care of the motherand fetus,resuscitation levels of doctors and nurses,reduce birth of prematures and low-birth-weight infants.Pay attention to keep warm,reduce cold injury and the organic impairment of newborns with asphyxia,and then lower the mortality of newborns.