| 甲状旁腺素相关肽与肿瘤 |
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| 引用本文： | 杨明妍,梁华晟.甲状旁腺素相关肽与肿瘤[J].国际肿瘤学杂志,2013,40(7):489-491. |
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| 作者姓名： | 杨明妍 梁华晟 |
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| 作者单位： | 536000,北海市内分泌代谢研究所 |
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| 基金项目： | 北海市科学研究与技术开发项目 |
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| 摘 要： | 甲状旁腺素相关肽(PTHrP)参与调节钙磷代谢和多器官的生长发育,在恶性肿瘤发生骨转移和高钙血症过程中发挥重要作用.越来越多的研究证实PTHrP可以由多种类型的肿瘤细胞分泌,参与调节肿瘤细胞的增殖、侵袭,并与患者预后密切相关,为肿瘤治疗提供了新的靶点.
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| 关 键 词： | 肿瘤 高钙血症 肿瘤转移 甲状旁腺素相关肽 |
Parathyroid hormone related peptide and tumor |
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| YANG Ming-yan
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LIANG Hua-sheng.Parathyroid hormone related peptide and tumor[J].Journal of International Oncology,2013,40(7):489-491. |
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| Authors: | YANG Ming-yan LIANG Hua-sheng |
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| Institution: | Institute of Endocrine and Metabolic Diseases, Guangxi Beihai, Beihai 536000, China |
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| Abstract: | The parathyroid hormone related peptide (PTHrP) participates in regulating calcium and phosphorus metabolism and multiple organ growth, and plays an important role in the processes of malignant tumor bone metastasis and hypercalcemia. Currently, more and more researches have confirmed that PTHrP can be secreted by a variety of types of tumor cells. PTHrP participates in regulating tumor cell proliferation and invasion, and it is closely related to the prognosis of patients, which provides a new target of cancer treatment. |
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| Keywords: | Neoplasms Hypercalcemia Neoplasm metastasis Parathyroid hormone related peptide |
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