| 精子相关抗原SPAG9与肿瘤 |
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| 引用本文： | 陈杰,王昌,徐忠华.精子相关抗原SPAG9与肿瘤[J].国际肿瘤学杂志,2011,38(6):421-423. |
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| 作者姓名： | 陈杰 王昌 徐忠华 |
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| 作者单位： | 山东大学齐鲁医院泌尿外科,济南,250012 |
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| 基金项目： | 山东省自然科学基金资助项目 |
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| 摘 要： | 精子相关抗原9(SPAC9)属于c-Jun N端激酶相互作用蛋白家族的新成员,主要在精卵融合和丝裂原活化蛋白激酶信号传导通路中发挥作用.研究表明,SPAG9与人类多种恶性肿瘤的生物学行为密切相关,在肿瘤发生发展过程中起重要作用.
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| 关 键 词： | 抗原 肿瘤 信号传导 |
Sperm associated antigen 9 and cancer |
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| CHEN Jie,WANG Chang,XU Zhong-hua.Sperm associated antigen 9 and cancer[J].Journal of International Oncology,2011,38(6):421-423. |
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| Authors: | CHEN Jie WANG Chang XU Zhong-hua |
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| Abstract: | Sperm associated antigen 9(SPAG9),a new member of the c-Jun NH2-terminal kinase (JNK)interacting protein(JIP)family. plays a role in sperm-egg fusion and mitogen-activated protein kinase (MAPK)signaling pathway.Researches have shown that SPAG9 is closely related to the biological behavior of human malignant tumors, and plays an important role in the development of tumor. |
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| Keywords: | Antigens Neoplasms Signal transduction |
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