Relationship Between Breast Density,Breast Cancer Subtypes,and Prognosis期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

按检索

Relationship Between Breast Density,Breast Cancer Subtypes,and Prognosis

Institution:	1. Department of Radiology, St. Luke''s International Hospital, Chuo-ku, Tokyo, Japan;2. Graduate School of Public Health, St. Luke''s International University, Chuo-ku, Tokyo, Japan;3. Department of Breast Surgical Oncology, St. Luke''s International Hospital, Chuo-ku, Tokyo, Japan;4. Department of Pathology, St. Luke''s International Hospital, Chuo-ku, Tokyo, Japan;1. Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard University, Boston, MA;2. Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH;3. Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ;4. Department of Surgery, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ;1. Department of Internal Medicine, University Hospitals Leuven, Leuven, Belgium;2. Department of General Medical Oncology/Multidisciplinary Breast Center, University Hospitals Leuven – Campus Gasthuisberg, Leuven, Belgium;3. Surgical Oncology/Multidisciplinary Breast Center, University Hospitals Leuven – Campus Gasthuisberg, Leuven, Belgium;4. Department of Gynaecological Oncology/Multidisciplinary Breast Center, University Hospitals Leuven – Campus Gasthuisberg, Leuven, Belgium;5. Department of Radiotherapy/Multidisciplinary Breast Center, University Hospitals Leuven – Campus Gasthuisberg, Leuven, Belgium;6. Department of Public Health and Primary Care, Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Catholic University Leuven, Leuven, Belgium;1. The University of Cambridge, The Old Schools, Cambridge, United Kingdom;2. Cambridge University Hospitals, Breast Unit, Cambridge Biomedical Research Centre, Cambridge, United Kingdom;1. Cancer Biology Laboratory, Department of Biochemistry and Bioinformatics, GITAM School of Science, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, India;2. Department of Bioscience and Biotechnology, Banasthali University, Vanasthali, Rajasthan, India;3. Department of Hematology and Oncology, School of medicine, University of Alabama, Birmingham, Birmingham, AL;1. Department of Bioresources, School of Biological Sciences, University of Kashmir, Srinagar-190006, J&K India;2. Department of Medical Laboratory Sciences, CAMS, Majmaah University, Almajmaah, KSA;3. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, KSA;4. Department of Translational Medicine, Research Branch, Sidra Medicine, Doha, Qatar;5. Department of Diagnostic Imaging, St. jude Children''s Research Hospital, Memphis, TN;6. Department of Biotechnology, School of Life Sciences, Central University of Kashmir, Ganderbal, J&K, India

Abstract:	BackgroundIn the United States, Europe, and Asia, a consensus has been reached that there is a higher risk of breast cancer in high density breasts. However, there are some contrary reports that suggest the absence of an association between breast composition and breast cancer subtype; thus, there is conflicting evidence. The purpose of this study was to investigate trends in the incidence of breast cancer subtypes according to breast composition and analyze the survival rates in Japanese women.Patients and MethodsBetween 2007 and 2008, 1258 Japanese patients with invasive breast cancer who underwent mammography and obtained a pathological diagnosis in our institution were included in the study. We compared cancer subtypes with breast composition types (dense and non-dense breast), and classified them based on initial mammography findings. Information on 5- and 10-year survival rates was collected by chart review for patients with dense and nondense breasts. Statistical analysis was performed using the Pearson's chi-square test for breast composition and cancer subtype. The effect of breast composition on mortality was examined using a multivariate Cox proportional hazards model, and adjusted hazard ratios were calculated.ResultsNo significant difference was found between breast cancer subtype and breast composition (P = .08). Five-year (log-rank test, P = .09) and 10-year (log-rank test, P = .31) survival rates were not significantly different between breast composition types.ConclusionThere was no significant association between breast composition and cancer subtypes. There was also no significant difference in the prognosis between patients with and without dense breasts.

Keywords:	Breast density BI-RADS"} {"#name":"keyword" "$":{"id":"pc_ZMT0Q7c3Zq"} "$$":[{"#name":"text" "_":"Breast Imaging-Reporting and Data System HR"} {"#name":"keyword" "$":{"id":"pc_lpcTYuO4RN"} "$$":[{"#name":"text" "_":"Hormone receptor HER-2"} {"#name":"keyword" "$":{"id":"pc_y0OFISknxA"} "$$":[{"#name":"text" "_":"Human epidermal growth factor Type 2 BC"} {"#name":"keyword" "$":{"id":"pc_eArjnh5mKx"} "$$":[{"#name":"text" "_":"Breast cancer TNBC"} {"#name":"keyword" "$":{"id":"pc_8qfzUrkIHU"} "$$":[{"#name":"text" "_":"Triple negative breast cancer ER"} {"#name":"keyword" "$":{"id":"pc_EjtQEDbODd"} "$$":[{"#name":"text" "_":"Estrogen reception PgR"} {"#name":"keyword" "$":{"id":"pc_UxHOrLtvTG"} "$$":[{"#name":"text" "_":"Progesterone receptor
本文献已被 ScienceDirect 等数据库收录！

设为首页 | 免责声明 | 关于勤云 | 加入收藏