| 非小细胞肺癌脑转移患者放疗后的生存状况及预后分析 |
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| 引用本文： | 毕良文,张丽珍,赵维勇,赵滑峰,时前军,秦亮.非小细胞肺癌脑转移患者放疗后的生存状况及预后分析[J].现代肿瘤医学,2011,19(8):1534-1536. |
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| 作者姓名： | 毕良文 张丽珍 赵维勇 赵滑峰 时前军 秦亮 |
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| 作者单位： | 南京医科大学第二附属医院放疗科,江苏,南京,210011 |
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| 摘 要： | 目的:探讨非小细胞肺癌脑转移放疗后生存状况及预后的相关因素。方法:回顾性分析本院2004年9月-2007年12月58例非小细胞肺癌脑转移患者的临床资料,Kaplan Meier法进行生存率统计,并进行Log-rank时序检验,利用比例风险模型(Cox模型)进行多因素分析,筛选相关因素。结果:非小细胞肺癌脑转移患者放疗后的1年生存率为37.9%,2年生存率13.8%。单因素分析结果显示,患者的KPS评分、脑转移数目、有无颅外转移、原发病灶控制情况及放疗方法对生存期有影响(P<0.05),多因素分析显示,KPS评分、脑转移灶数目是预后的独立因素(P<0.05)。结论:患者的KPS评分、脑转移灶数目、原发病灶控制情况、有无颅外转移及放疗方式是非小细胞肺癌脑转移的预后因素。KPS≥70分,脑转移灶为单发是肺癌脑转移患者良好的独立预后因素,这些患者的生存期较长,是潜在的治疗获益者。
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| 关 键 词： | 肺癌 转移 预后分析 |
Survival and prognostic factors of NSCLC patients with brain metastases after brain radiotherapy |
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| BI Liangwen,ZHANG Lizhen,ZHAO Weiyong,ZHAO Huafeng,SHI Qianjun,QIN Liang.Survival and prognostic factors of NSCLC patients with brain metastases after brain radiotherapy[J].Journal of Modern Oncology,2011,19(8):1534-1536. |
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| Authors: | BI Liangwen ZHANG Lizhen ZHAO Weiyong ZHAO Huafeng SHI Qianjun QIN Liang |
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| Institution: | BI Liangwen,ZHANG Lizhen,ZHAO Weiyong,ZHAO Huafeng,SHI Qianjun,QIN Liang Department of Raidotherapy,The Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011,China |
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| Abstract: | Objective:To study the survival and prognostic factors of NSCLC patients with brain metastases.Methods: The clinical data of 58 NSCLC patients with brain metastases in our hospital from 2004 to 2009 were retrospectively reviewed.Multivariate analysis was performed with Cox's proportion risk model.Survival analysis and log-rank test was performed with Kaplan-Meier method.Results: Univariate analysis showed that patient's performance status,age,number of brain metastatases,absence or presence of extracranial ... |
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| Keywords: | lung cancer metastasis prognostic analysis |
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