介入治疗联合其他治疗手段在肝内胆管癌治疗中的应用及进展

肝内胆管癌（intrahepatic cholangiocarcinoma,ICC）是一种高度侵袭性的恶性肿瘤，由于其病因复杂、起病隐匿，大多数患者预后较差，单一治疗手段的治疗效果不尽人意。因此，对于ICC多学科综合治疗模式的探索及研究至关重要。而介入治疗凭借多样化的治疗方式及更高的患者耐受性可以与多种治疗手段联合应用。本文探讨了介入治疗联合外科治疗、介入治疗联合全身化疗、介入治疗联合免疫治疗及靶向治疗在ICC中的应用以及取得的成果，并对未来ICC的治疗方向做出展望。

Application and progress of interventional therapy combined with other treatments in intrahepatic cholangiocarcinoma

Intrahepatic cholangiocarcinoma(ICC) is a kind of highly invasive malignant tumor.The effects of one single treatment in the past were unsatisfactory,in addition,its complex etiology and insidious onset process lead to a poor outcome of most patients.Therefore,it's very important to explore and study the multidisciplinary treatment mode of ICC.By right of its flexible treatment and higher patient tolerance，interventional therapy can be combined with a variety of treatment methods.The study progresses on the application and achievements of the combination of interventional therapy and surgical therapy,interventional therapy and systemic chemotherapy,interventional therapy and immunotherapy or targeted therapy,moreover,we look forward to the prospect of the treatment in ICC.