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化疗相关心脏毒性问题研究进展
引用本文:苏毅馨1,朱世杰1,高业博1,薛 鹏1,褚雪镭1,谢飞宇2,于成凤1,张 鑫2. 化疗相关心脏毒性问题研究进展[J]. 现代肿瘤医学, 2022, 0(17): 3253-3256. DOI: 10.3969/j.issn.1672-4992.2022.17.039
作者姓名:苏毅馨1  朱世杰1  高业博1  薛 鹏1  褚雪镭1  谢飞宇2  于成凤1  张 鑫2
作者单位:1.中国中医科学院望京医院,北京 100102;2.北京中医药大学,北京 100029
基金项目:北京市自然科学基金资助(编号:7204332)
摘    要:化疗作为肿瘤治疗手段的基石之一,可引起心力衰竭、冠脉病变、瓣膜病、心律失常等心脏毒性事件,其相关近期、远期心脏毒性问题均需受到临床医生重视。近年随着肿瘤心脏病学交叉学科的发展,化疗药物相关心肌损伤问题在病理生理机制、诊断、治疗等方面均取得了一定进展,但仍然存在诸多问题。该综述从不同化疗药物引起心血管事件的流行病学、临床特点、机制、诊断及治疗策略方面简要介绍其心脏毒性的诊治问题,为临床实践提供参考。

关 键 词:化疗  心脏毒性  研究进展

Advances on chemotherapy-related cardiotoxicity
SU Yixin1,ZHU Shijie1,GAO Yebo1,XUE Peng1,CHU Xuelei1,XIE Feiyu2,YU Chengfeng1,ZHANG Xin2. Advances on chemotherapy-related cardiotoxicity[J]. Journal of Modern Oncology, 2022, 0(17): 3253-3256. DOI: 10.3969/j.issn.1672-4992.2022.17.039
Authors:SU Yixin1  ZHU Shijie1  GAO Yebo1  XUE Peng1  CHU Xuelei1  XIE Feiyu2  YU Chengfeng1  ZHANG Xin2
Affiliation:1.Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China; 2.Beijing University of Chinese Medicine,Beijing 100029,China.
Abstract:As one of the cornerstones of tumor therapies,chemotherapy can cause heart failure,coronary artery disease,valvular disease,arrhythmia and so on.Its related acute and long cardiotoxicity need to be paid attention by clinicians.With the development of interdisciplinary oncology cardiology in recent years,progresses have been made in mechanism,diagnosis and treatment of chemotherapy-related myocardial injury,but there are still many problems that need to be solved.This review briefly introduces the diagnosis and treatment of cardiotoxicity from the aspects of epidemiology,clinical characteristics,mechanism research,diagnosis and treatment strategy of cardiovascular events caused by chemotherapy,so as to provide reference for clinical practice.
Keywords:chemotherapy   cardiotoxicity   advances
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