| 侵袭性NK细胞白血病1例并文献复习 |
| |
| 引用本文： | 侯艳秋,王建宁,宋敏,张柳波,孟庆齐. 侵袭性NK细胞白血病1例并文献复习[J]. 现代肿瘤医学, 2010, 18(1) |
| |
| 作者姓名： | 侯艳秋 王建宁 宋敏 张柳波 孟庆齐 |
| |
| 作者单位： | 南京医科大学第二附属医院血液科,江苏,南京,210011 |
| |
| 摘 要： | 目的:提高对侵袭性NK细胞白血病(ANKL)的认识.方法:报告1例ANKL患者并结合文献进行复习.结果:患者高热、肝脾肿大、进行性血细胞减少、外周血大颗粒淋巴细胞异常增多、骨髓中异常细胞增多并伴吞噬血细胞现象等,白血病细胞免疫表型为CD2、CD56阳性,CD3、CD4、CD8和CD57阴性,临床进展迅速.结论:ANKL为一种少见疾病,除临床表现外,诊断时需结合白血病细胞的免疫表型并需注意与其他相关疾病的鉴别,该病常呈侵袭性进展,治疗效果欠佳,预后极差.
|
| 关 键 词： | 白血病 NK细胞 侵袭性 |
Aggressive NK cell leukemia:A case report and literature review |
| |
| HOU Yan-qiu,WANG Jian-ning,SONG Min,ZHANG Liu-bo,MENG Qing-qi. Aggressive NK cell leukemia:A case report and literature review[J]. Journal of Modern Oncology, 2010, 18(1) |
| |
| Authors: | HOU Yan-qiu WANG Jian-ning SONG Min ZHANG Liu-bo MENG Qing-qi |
| |
| Affiliation: | HOU Yan-qiu,WANG Jian-ning,SONG Min,ZHANG Liu-bo,MENG Qing-qi Department of Hematology,Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011,China. |
| |
| Abstract: | Objective:To improve the recognition of aggressive NK cell leukemia(ANKL).Methods:A case of ANKL was discussed with the review of related articles.Results:The patient had following characters:high fever,hepatosplenomegaly,pancytopenia,increased large granular lymphocyte(LGL)in peripheral blood and abnormal cells in marrow.The hemophagocytes were observed in marrow.The immunophenotypes of leukemic cells were CD2+,CD56+,CD3-,CD4-,CD8-,CD57-.This disease developed very quickly.Conclusion:As ANKL is rare,its di... |
| |
| Keywords: | Leukemia NK cell aggressive |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
