| 白藜芦醇对胃癌细胞HGC27细胞周期的影响 |
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| 引用本文： | 王长本,李良琼,孟凡萍. 白藜芦醇对胃癌细胞HGC27细胞周期的影响[J]. 现代肿瘤医学, 2010, 18(1) |
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| 作者姓名： | 王长本 李良琼 孟凡萍 |
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| 作者单位： | 重庆三峡中心医院,重庆,万州,404000 |
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| 基金项目： | 重庆市卫生局科技计划项目，重庆市万州区科研项目 |
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| 摘 要： | 目的:研究白藜芦醇对胃癌细胞株HGC27细胞细胞周期的影响.方法:不同浓度的白藜芦醇作用于HGC27细胞,用流式细胞术分析细胞周期.结果:白藜芦醇作用后,HGC27细胞的增殖速度减缓,DNA合成减少.白藜芦醇在较低浓度时即可诱导G0/G1阻滞.结论:白藜芦醇可诱导胃癌细胞发生G0/G1阻滞,S期减少.
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| 关 键 词： | 白藜芦醇 细胞周期 胃癌 HGC27细胞 |
Effect of Resveratrol on the gastric carcinoma cells HGC27 |
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| WANG Chang-ben,LI Liang-qiong,MENG Fan-ping. Effect of Resveratrol on the gastric carcinoma cells HGC27[J]. Journal of Modern Oncology, 2010, 18(1) |
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| Authors: | WANG Chang-ben LI Liang-qiong MENG Fan-ping |
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| Affiliation: | WANG Chang-ben,LI Liang-qiong,MENG Fan-ping Chongqing Three Gorge Hospital,Chongqing 404000,China. |
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| Abstract: | Objective:To study the effects of Resveratrol on the growth,development,cell cycle and apoptosis of gastric carcinoma cells HGC27.Methods:Cells were treated by different concentration of resveratrol,and analyze cell cycle by flow cytometry.Rusults:After the treatment with Resveratrol,HGC27 cells proliferated more slowly.The synthesis of DNA decreased.Resveratrol at low concentration can induce fast and reversible blockage at phase S.Conclusion:Resveratrol could induce gastric carcinoma cells apoptosis.Suita... |
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| Keywords: | resveratrol cell cycle gastric carcinoma HGC27 cells |
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