粪便免疫化学检测结果与体重、血脂等的相关性分析

目的:探讨粪便免疫化学检测结果特点及与体重、血脂等的相关性。方法:选取2019年1月至12月于中国医科大学附属盛京医院体检中心完善粪便免疫化学检测的人群1249例为研究对象,采用乳胶凝集免疫比浊法对其进行粪便潜血检测,并记录其年龄、病史、血压、血脂、血糖、血尿酸等一般资料。结果:粪便免疫化学检测阳性者212例,阳性率为16.97%,男性阳性率高于女性(P<0.05)。青年组和老年组粪便免疫化学检测阳性率与中年组比较,差异具有统计学意义(P<0.05),而青年组和老年组之间差异没有统计学意义(P>0.05)。粪便免疫化学检测阳性的单因素分析发现,收缩压、舒张压、体质量指数、血糖空腹、甘油三酯、高密度胆固醇、低密度胆固醇、载脂蛋白B、血尿酸差异有统计学意义(P<0.05)。Logistic回归分析结果显示,体质量指数、甘油三酯、高密度胆固醇、低密度胆固醇为粪便免疫化学检测阳性的危险因素(P<0.05)。结论:人群中超重或肥胖、血脂异常是粪便免疫化学检测阳性的重要风险因素。

Analysis of the relationship between fecal immunochemical test and weight,blood lipid,etc.

Objective:To investigate the characteristics of fecal immunochemical test results and their correlation with weight,blood lipid,etc.Methods:A total of 1249 patients who completed the screening of colorectal cancer in the physical examination center of Shengjing Hospital Affiliated to China Medical University from January to December 2019 were selected as the study objects.The fecal immunochemical test(FIT)was conducted by latex agglutination immunoturbidimetry,and the general data of their age,medical history,blood pressure,blood lipid,blood glucose,and blood uric acid were recorded.Results:There were 212 cases of positive colorectal cancer screening,with the positive rate of 16.97%,and the positive rate of males was higher than that of females(P<0.05).The positive rate of colorectal cancer screening in the youth group and the elderly group compared with middle-aged group was statistically significant(P<0.05),but the difference between the youth group and the elderly group was not statistically significant(P>0.05).Single factor analysis of colorectal cancer screening positive found that the difference of systolic blood pressure(SBP),diastolic blood pressure(DBP),body mass index(BMI),fasting blood glucose(FBG),triglyceride(TG),high density cholesterol(HDL),low density cholesterol(LDL)and apolipoprotein B(Apol-B),blood uric acid(UA)was statistically significant(P<0.05).Logistic regression analysis results showed that BMI,TG,HDL,LDL were the risk factors for fecal immunochemical test positive(P<0.05).Conclusion:Overweight or obesity,and dyslipidemia are important risk factors for fecal immunochemical test positive.