回顾性分析颅内肿瘤患者术后感染危险因素

目的:了解神经外科颅内肿瘤切除患者术后相关感染（HAI）的发生情况及其危险因素，为制定干预措施提供理论依据。方法:收集 2017 年1月至2018年12月1 049例颅脑手术患者的临床资料，根据术后是否发生颅内感染将患者分为感染组 91例和非感染组958例。对两组患者进行临床资料的单因素和多因素logistic回归分析。结果:颅内肿瘤患者术后医院感染率为8.67%。两组在年龄、性别、职业、文化程度、民族、药物过敏、切口等级等方面比较差异无统计学意义（P＞0.05），麻醉方式、手术等级、转科情况、住院天数和住院费用两方面比较差异有统计学意义（P＜0.05）；经过logistic多因素回归分析显示麻醉方式、住院天数是颅内肿瘤手术患者术后医院感染的独立危险因素，其OR及95％CI分别为5.173（2.738～9.774）、1.132（1.079～1.189）。结论:颅脑手术患者中HAI发生率较高，应根据危险因素采取有效预防和控制措施，以降低HAI的发生率。

Retrospective analysis of the risk factors of postoperative infection in patients with intracranial tumor

Objective:To investigate the occurrence of postoperative health care associated infection(HAI)and its risk factors in neurosurgical patients undergoing removal of intracranial tumor,so as to provide theoretical basis for formulating intervention measures.Methods:The clinical data of 1049 patients who were given craniocerebral surgery in our hospital from January 2017 to December 2018 were collected.According to whether postoperative intracranial infection occurred,the patients were divided into infection group of 91 patients and non-infection group of 958 patients.Univariate and multivariate logistic regression analysis were performed on the clinical data of the two groups of patients.Results:The incidence of postoperative HAI was 8.67%.The study showed that the differences in age,gender,occupation,education level,nationality,drug allergy,incision grade were no statistically significant(P>0.05).There were statistically significant difference in anesthesia mode,surgical grade,transfer status,length of stay and hospitalization expenses(P<0.05).Multivariate logistic regression analysis showed that anesthesia mode and length of stay were independent risk factors in neurosurgical patients.undergoing removal of intracranial tumor,OR and 95%CI were 5.173(2.738~9.774),1.132(1.079~1.189)respectively.Conclusion:The incidence of HAI in patients with craniocerebral operation is high,effective preventive and control measures according to risk factors should be strengthened to reduce the incidence of HAL.