超微血流成像技术在前列腺癌精准靶向穿刺活检中的应用

目的 探讨超微血流成像（SMI）技术在前列腺癌精准靶向穿刺活检中的应用价值。方法 87例临床拟诊断前列腺癌患者均经过第一次系统12点穿刺术1月后选择进行第二次穿刺活检方式，其中48例采用系统12点穿刺法，39例采用SMI精准靶向定位异常区域替代局部系统穿刺法。根据第一次穿刺病理组织学结果，分析两种方式在前列腺癌穿刺活检中的异同。结果 在良恶性病变中，前列腺体积的差异无统计学意义，血清PSA水平差异有统计学意义（t=2.045, P=0.04）；SMI组穿刺恶性20例，穿刺阳性率为51.28%，总穿刺456针；对照组穿刺恶性14例，穿刺阳性率为29.17%，总穿刺576针。两组穿刺阳性率、平均穿刺针点数差异有统计学意义（χ ²=4.420, P=0.036; t=13.18, P=0.000）。SMI组中恶性病理组织为79条，患者Gleason最高评分（7.2±0.4）分；对照组中恶性病理组织为64条，患者Gleason最高评分（6.5±0.4）分。两组单次取材阳性率、Gleason最高评分差异有统计学意义（χ ²=8.232, P=0.004; t=5.940, P=0.000）。结论 SMI技术引导前列腺癌穿刺活检可提高取材的阳性率。

Application of Superb Micro-vascular Imaging Technology in Guiding AccuratelyTargeted Biopsy of Prostate Cancer

Objective To investigate the application of superb micro-vascular imaging(SMI) technology in accurately targeted biopsy of prostate cancer. Methods One month after 87 patients with clinically suspected prostate cancer received the first systematic 12-points puncture, 48 patients received system 12-points puncture, 39 patients received SMI technology to accurately target abnormal areas replacing local system puncture. According to histo pathological confirmation of the first puncture, the results of two methods in prostate cancer biopsy were compared and analyzed. Results There was no significant difference in prostate volumes between patients with malignant and benign prostate diseases, and the difference in serum PSA levels was statistically significant(t=2.045, P=0.04). In the SMI group, 20 cases were malignant, puncture positive rate was 51.28%, and the total numbers of puncture were 456 needle points; in the control group, 14 cases were malignant, puncture positive rate was 29.17%, and the total numbers of puncture were 576 needle points; there were significant differences in puncture positive rate and the average numbers of puncture point between the two groups (χ ²=4.420, P=0.036; t=13.18, P=0.000). There were 79 cases of malignant pathological tissues and the highest Gleason scores were 7.2±0.4 in the SMI group; in the control group, there were 64 cases of malignant pathological tissues, and the highest Gleason scores were 6.5±0.4; there were significant differences between the two groups in the positive rate of single sampling and the highest Gleason score (χ ²=8.232, P=0.004; t=5.940, P=0.000). Conclusion SMI technology to guide prostate cancer biopsy could improve the positive rate of draw materials.