| 局部进展期直肠癌新辅助治疗策略研究进展 |
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| 引用本文： | 姜玉娟,周思成,裴炜,梁建伟,周志祥.局部进展期直肠癌新辅助治疗策略研究进展[J].肿瘤防治研究,2022,49(3):235-239. |
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| 作者姓名： | 姜玉娟 周思成 裴炜 梁建伟 周志祥 |
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| 作者单位： | 100021 北京，国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院结直肠外科 |
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| 摘 要： | 局部进展期直肠癌(LARC)的治疗极具挑战性,仅凭手术切除难以达到满意疗效,近年来LARC诊治倾向于多学科协作(MDT)模式,依托其出现的新辅助治疗策略是LARC诊治的里程碑式进展.目前,LARC首选疗法为新辅助放化疗联合全直肠系膜切除术.本文围绕LARC新辅助治疗主要方案作一综述,以期为临床诊疗提供参考.
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| 关 键 词： | 直肠癌 新辅助治疗 观察等待疗法 免疫治疗 |
| 收稿时间： | 2021-07-06 |
Advances in Neoadjuvant Therapy for Locally Advanced Rectal Cancer |
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| JIANG Yujuan,ZHOU Sicheng,PEI Wei,LIANG Jianwei,ZHOU Zhixiang.Advances in Neoadjuvant Therapy for Locally Advanced Rectal Cancer[J].Cancer Research on Prevention and Treatment,2022,49(3):235-239. |
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| Authors: | JIANG Yujuan ZHOU Sicheng PEI Wei LIANG Jianwei ZHOU Zhixiang |
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| Institution: | Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China |
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| Abstract: | The treatment of locally advanced rectal cancer (LARC) is extremely
challenging, and it is difficult to achieve satisfactory results with
surgical resection alone. In recent years, the diagnosis and treatment
of LARC tends to be multi-disciplinary (MDT) mode. The emerging
neoadjuvant treatment strategy is a milestone. At present, the preferred
treatment for LARC is neoadjuvant chemoradiotherapy combined with total
mesorectal excision. This article summarizes the main treatments of
LARC neoadjuvant therapy, hoping to provide reference for clinical
diagnosis and treatment. |
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| Keywords: | Locally advanced rectal cancer Neoadjuvant therapy Watch & wait therapy Immunotherapy |
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