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Primary central nervous system sarcoma with DICER1 mutation—treatment results of a novel molecular entity in pediatric Peruvian patients |
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| Authors: | Rosdali Y Diaz Coronado MD Martin Mynarek MD Christian Koelsche MD Pamela Mora Alferez MD Sandro Casavilca Zambrano MD Antonio Wachtel Aptowitzer MD Felix Sahm MD Andreas von Deimling MD Ulrich Schüller MD Michael Spohn MSc Dominik Sturm MD Stefan M Pfister MD Andres Morales La Madrid MD Raymundo Sernaque Quintana MD Gustavo Sarria Bardales MD Tatiana Negreiros Chinchihuara MD Luis Ojeda Medina MD Pamela Garcia-Corrochano Medina MD Danny A Campos Sanchez MD Jimena Ponce Farfan MD Stefan Rutkowski MD Juan L Garcia Leon MD |
| Institution: | 1. Pediatric Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru;2. Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;3. Department of Pathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany;4. Genetics Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru;5. Pathology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru;6. Pediatric Oncology Service, Anglo Americana Clinic, Lima, Peru;7. Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany
Clinical Cooperation Unit Neuropathology, German Cancer Research Center, Heidelberg, Germany;8. Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Research Institute Children's Cancer Center, Hamburg, Germany Institute of Neuropathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany;9. Research Institute Children's Cancer Center, Hamburg, Germany Bioinformatics Core Facility and Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;10. University Medical Center, Heidelberg, Germany Hopp Children's Cancer Center Heidelberg, Heidelberg, Germany Pediatric Glioma Research Group, German Cancer Research Center, Heidelberg, Germany;11. University Medical Center, Heidelberg, Germany Hopp Children's Cancer Center Heidelberg, Heidelberg, Germany Division of Pediatric Neurooncology, German Cancer Consortium and German Cancer Research Center, Heidelberg, Germany;12. Pediatric Oncology Department, Neuro Oncology Unit, Hospital San Joan De Deu, Barcelona, Spain;13. Radiology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru;14. Delgado Clinic, Auna, Lima, Peru Radiotherapy Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru;15. Radiotherapy Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru;16. Neurosurgery Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru;17. Neurosurgery Service, Anglo Americana Clinic, Lima, Peru;18. Pediatric Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru Delgado Clinic, Auna, Lima, Peru Pediatric Oncology Service, Anglo Americana Clinic, Lima, Peru |
| Abstract: | |
| Keywords: | central nervous system (CNS) pediatric Peru sarcoma somatic DICER1 mutation |