食管癌术后纵隔转移灶的放射治疗

目的探讨胸段食管癌根治术后纵隔转移灶放射治疗的意义和效果。方法回顾性分析76例食管癌根治术后3～18个月发生纵隔转移患者。转移灶<2cm11例，2～3?cm33例，>3cm32例。伴有颈淋巴结转移9例，伴脏器转移3例。放射治疗采用60Co常规分割照射，照射剂量10.8～75.0Gy。结果未完成治疗计划的9例患者均于照射后1年内死亡。照射剂量为50～75Gy患者1、2、3年生存率分别为75.0%（57/76）、27.6%（21/76）和9.2%（7/76）。结论食管癌根治术后发生纵隔转移进行放射治疗可以延长患者生存时间，照射剂量以组织量65～75Gy为宜。

Radiotherapy of mediastinal metastasis after radical operation in esophageal ca rcinoma

Objective　To study the significance of radiotherapy of mediastinal m etastasis after radical surgery for thoracic esophageal carcinoma. 　Methods　 Sevent y-six patients with esophageal carcinoma who developed mediastinal metastasis 3～ 18 months after radical surgery were retrospectively analyzed. The size of media stinal metastasis was <2?cm in 11 patients, 2～3?cm in 33 and >3?cm in 32 . Nine of these patients had metastasis in neck lymph nodes and 3 had distant metastasi s as well. Radiotherapy was given with a Cobalt 60 unit. The radiation dose rang ed from 10.8?Gy to 75.0?Gy by conventional fractionation. 　Results　 Nine patient s di d not finish radiotherapy and all of them died within one year of (after) treat ment. The mean of survival time was 4.9 months. Sixty-seven patients received radiati o n of 50～70?Gy. The corresponding overall survivals at 1, 2, and 3 years were 75.0% (57/76), 27.6% (21/76) and 9.2% (7/76), respectively. 　Conclusion　Radical radio therapy may improve the prognosis with an appropriate tumor dose of 65～75?Gy.