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HOXA5基因与肿瘤
引用本文:张艳君,贾秀红.HOXA5基因与肿瘤[J].国外医学(肿瘤学分册),2011(9):652-656.
作者姓名:张艳君  贾秀红
作者单位:滨州医学院附属医院儿科,256603
摘    要:HOXA5作为同源盒(HOX)基因家族的一员,在多器官中都有表达,具有调节基因表达、细胞分化和机体形态发生的功能,其结构和(或)功能异常与白血病、乳腺癌、脑血管瘤、肝细胞癌等肿瘤的发生密切相关。研究HOXA5与肿瘤的关系有助于肿瘤的诊断、治疗及预防。

关 键 词:基因  HOXA5  肿瘤  基因  同源盒

HOXA5 gene and tumor
ZHANG Yan-jun,JIA Xiu-hong.HOXA5 gene and tumor[J].Foreign Medical Sciences (Cancer Section),2011(9):652-656.
Authors:ZHANG Yan-jun  JIA Xiu-hong
Institution:. Department of Pediatrics, Affiliated Hospital of Binzhou Medical University, Binzhou 256603, China
Abstract:As a member of homeobox gene family, HOXA5 is expressed in many organs and can regulate gene expression, cell differentiation and morphogenesis. Its structure and (or) function abnormalities are closely related to the development of leukemia, breast cancer, brain hemangioma, hepatocellular carcinoma and so on. Researching the relationships between HOXA5 and tumors contributes to cancer diagnosis, treatment and prevention.
Keywords:Genes  HOXA5  Neoplasms  Genes  homeobox
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