| 甲孕酮对改善癌症患者化疗期间生活质量的临床观察 |
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| 引用本文： | 郭仁宏,黄富麟,吴罕莉,祝浩祥,宋依霖,孙蔚莉,郑秀立.甲孕酮对改善癌症患者化疗期间生活质量的临床观察[J].肿瘤基础与临床,1999(2). |
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| 作者姓名： | 郭仁宏 黄富麟 吴罕莉 祝浩祥 宋依霖 孙蔚莉 郑秀立 |
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| 作者单位： | 江苏省肿瘤医院肿瘤内科 |
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| 摘 要： | 目的为了改善癌症患者化疗期间生活质量。方法1991年12月至1994年12月期间，对30例癌症患者进行了甲孕酮（MPA）治疗的临床观察，设对照组30例。结果口服MPA的癌症患者普遍反映精神、食欲好转，体重有所增加，生活质量综合指数NPS评分较治疗前明显提高（80％，对照组为36．7％，P＜0．01），伴有痛疼的患者（计18例）的癌痛改善率治疗组为83．3％，显著高于对照组的41％。结论甲孕酮（MPA）可以广泛用于各种肿瘤的化疗期间，来改善患者生活质量。
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| 关 键 词： | 甲孕酮 肿瘤化疗 生活质量 |
Clinical Observation of Medroxyprogesterone Acetate in the Improvement of the Life Quality of Patients with Cancer During Chemotherapy |
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| Guo Renhong, Huang Fulin, Wu Hanli, et al.Clinical Observation of Medroxyprogesterone Acetate in the Improvement of the Life Quality of Patients with Cancer During Chemotherapy[J].journal of basic and clinical oncology,1999(2). |
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| Authors: | Guo Renhong Huang Fulin Wu Hanli |
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| Abstract: | Objective and Methods A group of 30 patients with cancer were treated with MPA to improve their life quality with a control group of 30 cases. Results The results indicated that the comprehensive index KPS of lise quality in thegroug of MPA was inreased apparently (80% versus 36.7%, P < 0.01) .83.3% of 18 cases in MPA group had pain releaved while 41% in the conrol group had pain releaved. The medial time for the blood cells decrease to the lowest was 12 and 16 days respectively (P > 0.05) . Conclusion The results show that MPA can be useful to various tumors in impoving life quality. |
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| Keywords: | Medroxyprogesterone Acetate tumor chemotherary life quality |
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