| EBV相关性胃癌中EB病毒基因表达研究进展 |
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| 引用本文： | 杜云,俞霞,季明芳.EBV相关性胃癌中EB病毒基因表达研究进展[J].中国肿瘤临床,2017,44(9):444-448. |
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| 作者姓名： | 杜云 俞霞 季明芳 |
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| 作者单位： | ①.中山大学附属中山医院，中山市肿瘤研究所（广东省中山市 528400） |
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| 基金项目： | the National Natural Science Foundation of China (No. 81572062)
本文课题受国家自然科学基金项目(81572062) |
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| 摘 要： | EB病毒（Epstein-Barr virus，EBV）是胃癌发生的生物学病因之一，EBV相关性胃癌（EBV associated gastric carcinoma，EB-VaGC）具有独特的临床病理学特征，其预后相对较好，因此EBV导致胃癌的机制研究也备受关注。近年来，随着分子生物学技术的发展，EBVaGC组织中EBV病毒基因表达的研究逐渐增多，为EBVaGC的诊断、治疗和预防提供了一定的理论依据。本文就EBVaGC组织中EBV病毒基因的表达进行综述。
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| 关 键 词： | EB病毒 胃癌 EBV相关性胃癌 基因 |
| 收稿时间： | 2017-02-01 |
Research progress on expression of Epstein-Barr virus genes in EBV associated gastric carcinoma |
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| Yun DU,Xia YU,Mingfang JI.Research progress on expression of Epstein-Barr virus genes in EBV associated gastric carcinoma[J].Chinese Journal of Clinical Oncology,2017,44(9):444-448. |
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| Authors: | Yun DU Xia YU Mingfang JI |
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| Institution: | ①.Cancer Research Institute of Zhongshan City, Zhongshan Hospital of Sun Yat-sen University, Zhongshan 528400, China②.Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou 510000, China |
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| Abstract: | Epstein-Barr virus (EBV) is a biological factor associated with gastric carcinoma. The prognosis of EBV-associated gastric car-cinoma (EBVaGC) is good because of its distinct clinicopathological features. The pathogenesis mechanism of EBVaGC is extensively in-vestigated at present. The development of molecular techniques has stimulated the research on the expression of EBV genes in EB-VaGC, thereby providing a theoretical foundation on the diagnosis, therapy, and prevention of EBVaGC. This article reviewed present research advances in EBV genes in EBVaGC. |
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| Keywords: | Epstein-Barr virus gastric carcinoma EBVaGC gene |
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