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Results of Cemented Posterior-Stabilized Total Knee Arthroplasty in Obese Patients With an Average 10-Year Follow-Up
Institution:1. Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY;2. Department of Orthopaedic Surgery, University of Louisville, Louisville, KY;3. UofL Physicians - Orthopedic Group, Louisville, KY;4. Department of Orthopaedic Surgery, University of Louisville, Adult Reconstruction Program, Louisville, KY;1. Department of Orthopaedic Surgery, Lenox Hill Hospital, Northwell Health, New York, NY;2. Department of Orthopaedic Surgery, Cleveland Clinic Cleveland, OH;3. Department of Orthopaedic Surgery, SUNY Downstate Brooklyn, New York, NY;4. Department of Orthopaedic Surgery, Johns Hopkins Medical Center Baltimore, MD;1. Division of Orthopaedics, Midwest Orthopaedics at Rush, Rush University Medical Center, Chicago, IL;2. Department of Orthopaedic Surgery and Physical Rehabilitation, Medical University of South Carolina, Charleston, SC;3. Department of Orthopaedic Surgery and Rehabilitation, Iowa University Hospitals and Clinics, Iowa City, IA
Abstract:BackgroundObese and morbidly obese patients undergoing primary total knee arthroplasty (TKA) place significant stress at the bone-cement-implant interface over the life of the patient. The purpose of this study is to evaluate results of cemented, posterior-stabilized TKA in obese and morbidly obese patients at an average follow-up of 10 years.MethodsRetrospective study of 181 patients who had a cemented, posterior-stabilized TKA between 2000 and 2013 with body mass index >35 at the time of surgery was conducted. Clinical data and radiographs were evaluated along with survivorship, complications, and revisions. Minimum follow-up was 5 years with an average follow-up of 10 years.ResultsThere were 135 women and 46 men in the study, with mean age of 60.2 years (range 43-80), mean body mass index of 42.0 (range 35.1-66.1), and an average follow-up of 10 years (range 5-18). There were a total of 39 failures (22%) that underwent revision TKA surgery with mean time to revision of 8 years. Failures included 25 (14%) cases of aseptic loosening; 9 (5%) polyethylene wear; 2 (1%) prosthetic joint infection; and 3 additional revisions for instability, pain, and stiffness. There were a total of 11 cases of isolated tibial component loosening and 13 for both tibial and femoral loosening. Survivorship at 15 years with aseptic loosening as the endpoint was 86.7%, and for all causes 79.6% at 15 years.ConclusionAseptic loosening is the leading cause of failure following TKA in obese and morbidly obese patients with decreasing survivorship from 96.1% to 91.2% and 86.7% at 5, 10, and 15 years, respectively.
Keywords:primary TKA  cemented  morbid obesity  aseptic loosening  survivorship
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