| 维持性血液透析对不同年龄组尿毒症患者热休克蛋白70表达的影响 |
| |
| 引用本文： | 刘琨,费秀丽,叶悦,沈冰,张骢.维持性血液透析对不同年龄组尿毒症患者热休克蛋白70表达的影响[J].国际移植与血液净化杂志,2011,9(3):23-26. |
| |
| 作者姓名： | 刘琨 费秀丽 叶悦 沈冰 张骢 |
| |
| 作者单位： | 上海市第六人民医院金山分院肾内科,201500 |
| |
| 摘 要： | 目的 探讨血液透析对不同年龄段尿毒症患者血清热休克蛋白70的影响.方法 对2010年4月在我院进行维持性血液透析的尿毒症患者,根据年龄将92例患者分为3组(青年组、中年组、老年组).在透析前、后分别采用酶联免疫复合物法测定血清热休克蛋白70水平.结果 青年组透析前、后热休克蛋白70水平比较差异有统计学意义(P＜0.05...
|
| 关 键 词： | 尿毒症 血液透析 热休克蛋白70 |
Differential effect of maintenance haemodialysis on expression of heat shock protein 70 in different age groups of uraemic Patients |
| |
| LIU Kun,FEI Xiu-li,YE Yue,SHEN Bing,ZHANG Cong-chong.Differential effect of maintenance haemodialysis on expression of heat shock protein 70 in different age groups of uraemic Patients[J].International Journal of Transplantation and Hemopurification,2011,9(3):23-26. |
| |
| Authors: | LIU Kun FEI Xiu-li YE Yue SHEN Bing ZHANG Cong-chong |
| |
| Abstract: | Objective We investigated the effect of haemodialysis on serum levels of heat shock protein 70 (Hsp70) in patients with uraemia. Methods Patients undergoing maintenance haemodialysis (MHD) since April 2010 were divided into three groups according to their ages. Group Ⅰ, 34 young adults (l8-44yr); Group Ⅱ , 35 adults (45-59 yr); and group Ⅲ , 23 senior adults (68-88 yr). Enzyme-linked immunosorbent assay (ELISA) was used to measure the serum Hsp70 levels before and after haemodialysis. Results The serum level of Hsp70 protein was significantly lower in the young adult group (P ＜ 0.05) while there is no significant difference in Group Ⅱ (middle-aged) and IE (senior) ( ＞ 44 yr) ( P ＞ 0.05 respectively). Conclusion Monitoring HSP70 serum level in MHD patients may be very important in determining patients' tolerance to environmental stresses. |
| |
| Keywords: | Uraemia Haemodialysis Heat shock protein 70 |
| 本文献已被 万方数据 等数据库收录！ |
|
