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| rhBMP-2HACo复合材料异位诱导成骨中碱性磷酸酶活性的检测 | |
| 引用本文： | 蒋月桂,孙斌,苟建重,王宝彦,宋健玲,孙沫逸.rhBMP-2HACo复合材料异位诱导成骨中碱性磷酸酶活性的检测[J].中国美容医学,2010,19(4):521-523. |
| 作者姓名： | 蒋月桂 孙斌 苟建重 王宝彦 宋健玲 孙沫逸 |
| 作者单位： | 1. 西安交通大学医学院附属口腔医院牙体牙髓病科,陕西,西安,710004 2. 西安交通大学医学院附属口腔医院,陕西,西安,710004 3. 西安第四军医大学口腔医学院口腔颌面外科,陕西,西安,710032 |
| 基金项目： | 陕西省社发攻关计划资助项目[编号:2002K10-G2(11)];;西安交通大学口腔学院青年科研基金资助项目[编号:2002YG-6];;陕西省社发攻关计划资助项目[编号:2006K10-G3(5)] |
| 摘 要： | 目的：确定rhBMP-2/HA/Co复合制剂的生物活性,为其作为盖髓剂和根尖诱导剂提供理论依据。方法：用全自动生化仪检测rhBMP-2/HA/Co复合材料异位诱导成骨区样本单位湿重的碱性磷酸酶（ALP）活性,并与HA/Co组对照。结果：实验组样本的单位湿重碱性磷酸酶（ALP）活性的平均值均明显高于对照组。结论：rhBMP-2/HA/Co复合材料可作为一种新型的、具有良好生物活性的材料进一步研究,为将来的临床应用打下基础。 |
| 关 键 词： | rhBMP-2 Ⅰ型胶原 羟基磷灰石 生物活性 小鼠 碱性磷酸酶 |
Determining the ALP activity in ectopia osteogenesis of rhBMP-2/HA/Co compound |
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| JIANG Yue-gui,SUN Bin,GOU Jian-zhong,WANG Bao-yan,SONG Jian-ling,SUN Mo-yi.Determining the ALP activity in ectopia osteogenesis of rhBMP-2/HA/Co compound[J].Chinese Journal of Aesthetic Medicine,2010,19(4):521-523. | |
| Authors: | JIANG Yue-gui SUN Bin GOU Jian-zhong WANG Bao-yan SONG Jian-ling SUN Mo-yi |
| Institution: | 1.Department of Endodontics/a>;the Affiliated Stomatological Hospital/a>;Medical School of Xi'an Jiaotong University/a>;Xi'an 710004/a>;Shaanxi/a>;China/a>;2.The Affiliated Stomatological Hospital/a>;3.Department of Oral and Maxillofacial Surgery/a>;Stomatological College/a>;the Fourth Military Medical University/a>;Xi'an 710032/a>;China |
| Abstract: | Objective Determining the biological activity of rhBMP-2/HA/Co in order to use them in pulp capping and apexification.Methods Automatic Chemistry Analyzer be used to evaluating the ALP activity of every sample-unitwet-weight of rhBMP-2/HA/Co and HA/Co.Results The average value of ALP activity in all samples unit-wet-weight of rhBMP-2/HA/Co group were apparently higher than those of HA/Co group.Conclusion With fine biological activity,rhBMP-2/HA/Co compound can be studied furtherly to find out their applicat... |
| Keywords: | rhBMP-2 |
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