从肝论治原发性骨质疏松症的研究进展

骨质疏松症是一种以骨量低下,骨微结构损坏,导致骨脆性增加,易发生骨折为特征的全身性骨病。随着老龄化的加剧,老年人健康问题尤其是骨密度下降引起的骨质疏松越来越引起重视,但是目前原发性骨质疏松症的基础研究和临床诊治主要集中在"肾主骨,生髓"方面,肾虚是其主要病机,而肝对本病的研究和治疗相对较少。原发性骨质疏松症是一个复杂的、多因素导致的疾病,中医整体观要求我们不能一味地治疗某一症状或某一脏腑,要结合传统医学和现代医学分析其病因病机,辨证施治。从中医学肝对骨质疏松的认识到肝与骨质疏松的基础研究再到滋补肝肾的临床疗效,都说明肝对骨质疏松的重要性。补肾兼顾治肝,及早调肝养肝有益于防治骨质疏松症。

Research progress in the treatment of primary osteoporosis from the liver

Osteoporosis is a systematic disease characterized by low bone mass and bone microstructure damage, resulting in the increase of bone fragility and fracture. With the increase of society aging, osteoporosis due to the decrease of bone mineral density in the elderly is getting more and more attention. The current basic research of primary osteoporosis and clinical diagnosis and treatment mainly focus on the theory of kidney dominating bone and producing marrow, and kidney deficiency is the main pathogenesis. The research and treatment by the liver is relatively less. Primary osteoporosis is a complex and multi factor disease. The syndrome differentiation and treatment must combine traditional and modern medicine to analyze its etiology and pathogenesis, but not blindly treat a symptom or an organ. From the knowledge of traditional Chinese medicine, the experimental study on the relationship between the liver and osteoporosis, and the clinical observation of nourishing the liver and the kidney, liver plays an important role in primary osteoporosis. Nourishing the liver while nourishing the kidney at the early stage may benefit in the prevention and treatment of osteoporosis.