运动联合利塞膦酸钠治疗绝经后女性骨质疏松症疗效分析

目的观察广场舞运动联合补充利塞膦酸钠防治绝经后骨质疏松症的疗效。方法 168名绝经后骨质疏松症妇女随机分为实验组和对照组,实验组进行广场舞锻炼联合补充利塞膦酸钠治疗,对照组单纯予以补充利塞膦酸钠治疗。实验前及实验干预后6个月和12个月分别检测两组受试者腰椎L1-4、股骨颈部及Ward区骨密度、VAS疼痛评分、骨代谢指标以及不良反应。结果治疗6个月及12个月,两组患者VAS评分不同程度降低,其中以治疗组骨痛的治疗效果要明显优于对照组(P0.05)。治疗12个月后两组腰椎L1-4、股骨颈部及Ward区骨密度明显升高(P0.05),而治疗组明显高于对照组(P0.05)。治疗后6个月及12月,两组血清OC及NTX I较治疗前比较改善明显(P0.05),和对照组比较,治疗组血清OC及NTX I水平改变更为明显(P0.05);而两组不良反应无明显差异(P0.05)。结论广场舞运动结合补充利塞膦酸钠可以有效改善绝经后骨质疏松症,是一种合适的治疗方案。

Analysis of the efficacy of exercise combined with risedronate on osteoporosis in postmenopausal women

Objective To observe the effect of the combination of square dance and risedronate on the prevention and treatment of postmenopausal osteoporosis. Methods A total of 168 postmenopausal women with osteoporosis were randomly divided into experimental group and control group. The experimental group was treated with square dancing exercise combined with risedronate, and the control group was supplemented with risedronate alone. Bone mineral density (BMD) of the lumbar spine 1-4, femoral neck, and Ward''s, VAS pain score, bone metabolic index, and adverse reaction were measured before and 12 months after the experiment. Results After 6 and 12 months of the treatment, the VAS scores in both groups decreased in different degrees. The treatment effect of bone pain in the treatment group was significantly better than that in the control group (P<0.05). BMD of L1-4, femoral neck, and Ward''s area increased significantly in the two groups after 12 months of the treatment (P<0.05). The effect in the treatment group was significantly better than in the control group (P<0.05). The levels of serum OC and NTX I in the treatment group were significantly higher than those in the control group (P<0.05). There was no significant difference of adverse reaction between the two groups (P>0.05). Conclusion Square dance exercise combined with risedronate sodium effectively relieves postmenopausal osteoporosis, and it is a suitable treatment strategy.