无水乙醇联合泡沫硬化治疗儿童体表静脉畸形

目的观察无水乙醇联合泡沫硬化治疗体表静脉畸形(VM)患儿的有效性及安全性。方法回顾性分析接受DSA引导下无水乙醇联合聚桂醇泡沫硬化治疗的42例体表VM患儿,术后随访观察治疗效果及不良反应。结果共行79次硬化治疗,平均每例(1.1±0.2)次;总有效率97.62%(41/42)。79例次硬化治疗中,24例次术后疼痛明显,65例次术后病灶明显肿胀;12例次术后低热,对症治疗缓解或自行缓解;1例次术后局部坏死,经对症治疗3个月后瘢痕愈合;未发生过敏、异位栓塞及肺动脉高压等严重并发症。结论无水乙醇联合泡沫硬化治疗儿童体表VM安全有效。

Absolute ethanol combined with foam sclerotherapy for treatment of superficial venous malformations in children

Objective To observe the efficacy and safety of absolute ethanol combined with foam sclerotherapy for superficial venous malformations (VM) in children. Methods Data of 42 children with superficial VM were retrospectively analyzed. All children underwent DSA-guided absolute ethanol combined with lauromacrogol foam sclerotherapy, and then follow-up was conducted to observe the therapeutic effect and adverse reactions. Results All 79 sclerotherapy sessions were performed in 42 children, with an average of (1.1±0.2)times, and the total effective rate was 97.62% (41/42). Obvious postoperative pain occurred in 24 cases, while obvious postoperative swelling was observed in 65 cases. Low postoperative fever happened in 12 cases, which relieved after symptomatic treatment or self remission. Local necrosis occurred in 1 case and healed 3 months after symptomatic treatment and left scars. No severe complication such as allergy, ectopic embolism nor pulmonary hypertension occurred. Conclusion Absolute ethanol combined with foam sclerotherapy was safe and effective for treating superficial VM in children.