超声造影引导肝脏局灶性病变穿刺活检的临床应用价值

目的探讨超声造影引导肝脏局灶性病变穿刺活检的临床应用价值。方法共200例因肝脏局灶性病变行穿刺活检患者,随机分为实验组和对照组各100例,实验组行超声造影后常规超声引导下肝穿活检,对照组行常规超声引导下肝穿活检,比较两组总体及不同性质病变之间的一次取材满意率和诊断准确率。结果实验组总体一次取材满意率、诊断准确率分别为100%和98%,高于对照组的94%、91%（P〈0.05）。对直径≥5cm的病灶,实验组一次取材满意率100%,对照组97.56%（P〉0.05）,但实验组诊断准确率（100%）高于对照组（85.36%,P〈0.05）。对直径〈5cm的病灶,实验组一次取材满意率与诊断准确率（100%、96.42%）与对照组（93.22%、93.22%）比较均无明显差异（P〉0.05）。对肝癌（HCC）PEI治疗后穿刺,实验组一次取材满意率（100%）和对照组（89.74%）比较无明显差异（P〉0.05）,诊断准确率（100%）高于对照组（84.61%,P〈0.05）。实验组的平均穿刺次数（1.0±0）次]低于照组（1.12±0.41）次]。P〈0.05）。结论超声造影有助于提高肝脏局灶性病变穿刺活检的取材满意率及诊断准确率,减少穿刺次数,可提高较大病灶和PEI治疗后HCC穿刺活检的诊断准确率,减少假阴性结果。

Clinical application of percutaneous transhepatic biopsy of hepatic focal lesions guided by contrast-enhanced ultrasound

Objective To assess the clinical value of percutaneous transhepatic biopsy of focal hepatic lesions guided by contrast-enhanced ultrasound.Methods Two hundred patients with focal hepatic lesions were randomly divided into two groups.All patients underwent percutaneous transhepatic biopsy.One group underwent biopsy indirectly guided by contrast-enhanced ultrasound(experiment-group,one hundred cases),another group underwent biopsy guided by conventional ultrasound(control-group,one hundred cases).The biopsy a...