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TACE联合MRI引导下射频消融术治疗原发性肝癌
引用本文:陈仲武,林征宇,陈一平,陈锦.TACE联合MRI引导下射频消融术治疗原发性肝癌[J].中国介入影像与治疗学,2014,11(10):635-638.
作者姓名:陈仲武  林征宇  陈一平  陈锦
作者单位:福建医科大学附属第一医院介入科, 福建 福州 350005;福建医科大学附属第一医院介入科, 福建 福州 350005;福建医科大学附属第一医院介入科, 福建 福州 350005;福建医科大学附属第一医院介入科, 福建 福州 350005
摘    要:目的探讨TACE联合MRI引导下射频消融(RFA)治疗原发性肝癌(PHC)的疗效。方法纳入接受TACE联合MRI引导下RFA的PHC患者50例(88个病灶),治疗后随访AFP水平及肿瘤复发情况。结果平均随访(15.35±8.49)个月。治疗后2个月,患者AFP水平为(33.94±11.64)μg/L,明显低于治疗前水平(302.29±55.11)μg/L,P0.01]。共9个治疗病灶复发,治疗后0.5年、1年、1.5年、2年和2.5年治疗病灶累积复发率分别为0、0、1.14%(1/88)、4.55%(4/88)和10.23%(9/88);共35例患者复发,治疗后0.5年、1年、1.5年、2年和2.5年总累积复发率分别为4.00%(2/50)、32.00%(16/50)、52.00%(26/50)、64.00%(32/50)和70.00%(35/50)。结论 TACE联合MRI引导下RFA治疗PHC创伤小、治疗病灶复发率相对较低,具有较高临床应用价值。

关 键 词:  肝细胞  栓塞  治疗性  消融技术  磁共振成像
收稿时间:2014/3/23 0:00:00
修稿时间:2014/4/24 0:00:00

TACE combined with MRI-guided radiofrequency ablation in treatment of primary hepatic carcinoma
CHEN Zhong-wu,LIN Zheng-yu,CHEN Yi-ping and CHEN Jin.TACE combined with MRI-guided radiofrequency ablation in treatment of primary hepatic carcinoma[J].Chinese Journal of Interventional Imaging and Therapy,2014,11(10):635-638.
Authors:CHEN Zhong-wu  LIN Zheng-yu  CHEN Yi-ping and CHEN Jin
Institution:Department of Intervention, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China;Department of Intervention, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China;Department of Intervention, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China;Department of Intervention, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China
Abstract:Objective To evaluate the efficacy of TACE combined with MRI-guided radiofrequency ablation(RFA)in treatment of primary hepatic carcinoma(PHC).Methods A total of 50 patients with 88 lesions of PHC received TACE combined with MRI-guided RFA.The AFP level and the recurrence of PHC were assessed.Results The patients were followed up for(15.35±8.49)months.AFP level was(33.94±11.64)μg/L 2months after sequential operation,significantly lower than that before operation(302.29±55.11]μg/L,P〈0.01).PHC recurrence was noticed in 9primarily treated lesions,and the cumulative recurrence rate of primarily treated lesions was 0,0,1.14%(1/88),4.55%(4/88)and 10.23%(9/88)for 0.5,1,1.5,2and 2.5years after combined therapy,respectively.PHC recurrence was found in35 patients,and the total cumulative recurrence rate was 4.00%(2/50),32.00%(16/50),52.00%(26/50),64.00%(32/50)and 70.00%(35/50)for 0.5,1,1.5,2and 2.5years after combined therapy,respectively.Conclusion TACE combined with MRI-guided RFA is effective for treatment of PHC with small trauma and relative low recurrence,therefore having great clinical value.
Keywords:Carcinoma  hepatocellular  Embolization  therapeutic  Ablation techniques  Magnetic resonance imaging
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