经导管动脉化疗栓塞术联合部分性脾动脉栓塞术治疗原发性肝癌合并脾功能亢进

目的评价TACE联合部分性脾动脉栓塞术（PSE）治疗原发性肝癌（PHC）合并脾功能亢进的临床效果。方法对26例PHC合并脾功能亢进患者行TACE联合PSE治疗。术后采用肝脏CT、超声、肝功能、血常规及甲胎蛋白（AFP）检查,并进行随访。结果对26例患者共进行63次TACE、27次PSE治疗,全部治疗均获成功,无严重并发症。全部患者随访2个月,均生存;23例患者随访6个月,17例生存;13例患者随访12个月,9例生存;8例患者随访24个月,5例生存。结论 TACE联合PSE治疗PHC合并脾功能亢进可取得较好的临床效果。

Transcatheter arterial chemoembolization combined with partial splenic embolization for treatment of primary hepatocellular carcinoma associated with hypersplenism

Objective To evaluate the effect of TACE combined with partial splenic embolization (PSE) in the treatment of primary hepatocellular carcinoma (PHC) associated with hypersplenism. Methods Twenty-six PHC patients associated with hypersplenism underwent TACE and PSE. Following up was performed with liver ultrasound, CT scan, liver function, peripheral blood routine test and alfa fetoprotein. Results Sixty-three times of TACE and 27 times of PSE procedures were performed on 26 patients. All the interventional procedures were successful without serious complications. Twenty-six patients were followed up for 2 months after TACE and PSE, and all survived. Twenty-three patients were followed up for 6 months and 17 cases survived. Thirteen patients were followed up for 1 year and 9 cases survived. Eight patients were followed up for 2 years and 5 cases survived. Conclusion TACE combined with PSE is an effective method in treatment of PHC associated with hypersplenism.