310例慢性肾小球肾炎患者辨证规律研究

目的：通过对慢性肾小球肾炎患者（CKD2～3期）的中医证候分型、临床症状、中药疗效以及临床指标间相关性研究,探讨本病的中医证型分布特点,为进一步探索中药临床研究提供依据。方法：回顾性收集2008年～2011年入住我院肾病科的慢性肾小球肾炎患者的病史资料、中医临床症状、相关临床指标,运用统计分析方法研究慢性肾小球肾炎的中医辨证分型规律以及治疗方法。结果：（1）慢性肾小球肾炎的中医证型中以气阴两虚型、肝肾阴虚型常见;（2）脾肾阳虚型蛋白尿水平最高,差异具有统计学意义（P〈0.05）;（3）脾肾阳虚型中药治疗有效率最低（66.7%）。结论：慢性肾小球肾炎的中医证候以气阴两虚最为常见,脾肾阳虚型蛋白尿水平最高,治疗有效率最低。

Analysis on TCM Syndromes and Correlation Study of Clinical Indicators Related to 310 Chronic Kidney Diseases Patients

Objective：To investigate the distribution pattern of TCM syndrome, clinic features, treatment effects in patients with chronic kidney diseases （CKI） 2 - 3） and its relationship with the main clinical indexes to improve TCM diagnosis and treatment of the disease and supply possible evidences to researching the normalization of its TCM syndrome. Methods： According to retrospec- tive research of Zhejiang Shengli Tongde Hospitalized patients with CKD between 2008 ~ 2011 years, about history, clinical systems, relatived clinic test results, analyze to find out the diseases＇ TCM syndromes and treatment effective. Results： （ 1 ） Qi - yin deficiency and Liver - Kidney yin deficiency are common. （2） Protein in urine is most high in Spleen - Kidney syndrome （ P 〈 0.05 ）. （ 3 ） The treatment effect of yang- deficiency of spleen and kidney is lowest （66.7%）. Conclusion： Qi -yin deficiency is most common in CKD TCM syndromes. Yang - deficiency of spleen and kidney has highest protein urine and lowest treatment effect.