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肾嫌色细胞癌的超声造影表现
引用本文:雷丽,姚春晓,杨斌,傅宁华,魏淑萍,刘萍.肾嫌色细胞癌的超声造影表现[J].中华泌尿外科杂志,2011,32(4).
作者姓名:雷丽  姚春晓  杨斌  傅宁华  魏淑萍  刘萍
作者单位:南京大学医学院临床学院南京军区南京总医院超声诊断科,210002
基金项目:国家自然科学基金面上项目
摘    要:目的 分析肾嫌色细胞癌的超声造影特征,提高对该肿瘤的识别.方法 分析经手术病理证实的28例嫌色细胞癌超声造影资料,分析血供情况及造影特征,并进行时间-强度曲线参数分析.结果 28例嫌色细胞癌与肾皮质作参照均呈乏血供造影表现,且肿块呈不均匀增强,肿块局部呈"快进快出"造影表现,强化程度低于周围肾皮质,其中15例(54%)病灶内可出现辐射样分布的强回声带.时间-强度曲线显示嫌色细胞癌组曲线达峰绝对值、曲线下面积低于肾皮质(P<0.05),造影剂到达时间、达峰时间、曲线上升支斜率高于肾髓质组(P<0.05).结论 超声造影检查中,肾嫌色细胞癌瘤体内辐射状增强和瘤体呈乏血供型增强为诊断提供了依据.
Abstract:
Objective To discuss the imaging characteristics of chromophobic cell renal carcinoma (CCRC) and study the features on the contrast-enhanced ultrasound (CEUS). Methods The CEUS features of CCRC in 28 cases identified by pathology were reviewed. The blood supply and enhancement characteristic were observed and analyzed on time intensity curve parameters. Results The 28 cases of CCRC showed poor blood supply in contrast with the renal cortex. The CCRC presented with heterogeneity enhancement, part of the tumor took on a high wash-in and wash-out, and enhanced less intense than the surrounding renal cortex. The actinomorphous strong echo of the tumors might be revealed with CEUS in 15 cases (54%). The time intensity curve analysis demonstrated that the CCRCs' difference of peak intensity and area under the curve were lower than the renal cortex (P<0.05), but arrival time, time-to-peak and slope of ascending curve were higher than the renal medulla (P<0.05). Conclusion The actinomorphous enhancement and poor blood supply in the tumor of CEUS could provide diagnostic evidence for CRCC.

关 键 词:超声检查  超声造影    肾细胞  嫌色细胞癌

Contrast-enhanced ultrasound findings of chromophobic cell renal carcinoma
LEI Li,YAO Chun-xiao,YANG Bin,FU Ning-hua,WEI Shu-ping,LIU Ping.Contrast-enhanced ultrasound findings of chromophobic cell renal carcinoma[J].Chinese Journal of Urology,2011,32(4).
Authors:LEI Li  YAO Chun-xiao  YANG Bin  FU Ning-hua  WEI Shu-ping  LIU Ping
Abstract:Objective To discuss the imaging characteristics of chromophobic cell renal carcinoma (CCRC) and study the features on the contrast-enhanced ultrasound (CEUS). Methods The CEUS features of CCRC in 28 cases identified by pathology were reviewed. The blood supply and enhancement characteristic were observed and analyzed on time intensity curve parameters. Results The 28 cases of CCRC showed poor blood supply in contrast with the renal cortex. The CCRC presented with heterogeneity enhancement, part of the tumor took on a high wash-in and wash-out, and enhanced less intense than the surrounding renal cortex. The actinomorphous strong echo of the tumors might be revealed with CEUS in 15 cases (54%). The time intensity curve analysis demonstrated that the CCRCs' difference of peak intensity and area under the curve were lower than the renal cortex (P<0.05), but arrival time, time-to-peak and slope of ascending curve were higher than the renal medulla (P<0.05). Conclusion The actinomorphous enhancement and poor blood supply in the tumor of CEUS could provide diagnostic evidence for CRCC.
Keywords:Ultrasonography  Contrast-enhanced ultrasound  Carcinoma  renal cell  Chromophobic renal cell carcinoma
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