齿状突加冠综合征临床诊治研究进展

齿状突加冠综合征（crowned dens syndrome，CDS）是以齿状突周围发生“冠状”钙化沉积为主要影像学表现，以头颈上部急性发作的疼痛、僵硬、发热甚至出现颈髓压迫症状为主要临床表现的一组综合征，普遍被认为是晶体沉积病造成的。CDS的临床表现常常类似于脑膜炎，常常伴有血液中炎性标志物的升高，因此非常容易造成漏诊和误诊，临床上易被施以错误的或不必要治疗。目前CDS的诊断以CT中的影像学表现为“金标准”，治疗以NASIDs药物和皮质类固醇药物为主，其预后往往也是良好的，基本上发生此病的患者在3个月内其影像学表现完全消失。

Progress in diagnosis and treatment of crown dens syndrome

Crowned dens syndrome(CDS) is a major imaging manifestation of "coronary" calcified deposits around the odontoid,with pain,stiffness,fever,and even cervical cord compression in the upper head and neck. It was first described by Bouvet et al. in 1985,and the onset was generally thought to be caused by crystal deposition. The clinical manifestations of CDS are often similar to meningitis and often accompanied by an increase in inflammatory markers in the blood. As a result,it is very easy to obtain missed diagnosis and misdiagnosis,and it is clinically prone to obtain wrong or unnecessary treatment. At present,the diagnosis of CDS is based on the imaging findings in CT as a "golden standard". NASIDs drugs and corticosteroids are the main treatment. The prognosis is also generally good,and the imaging findings of the patients with the disease disappear completely within 3 months.