皮层体感诱发电位与脊髓型颈椎病患者脊髓功能相关性

目的研究皮层体感诱发电位(cortical somatosensory evoked potentials,CSEP)与脊髓型颈椎病(cervical spondylitic myelopathy,CSM)患者脊髓功能的相关性。方法 2008年7月—2012年5月在本院诊断为CSM的患者67例。记录CSM患者CSEP与颈段脊髓传导功能的相关指标,包括N13、N20潜伏期,N9~N20、N9~N13峰间潜伏期(interpeak latency,IPL),P13~N13、P20~N20峰-峰值(peak-peak amplitude,PPA)。记录患者日本骨科学会(Japanese Orthopaedic Association,JOA)评分。将CSEP记录值与JOA评分关系绘制成散点图,当观察到点分布有直线趋势,进行直线相关分析。结果 N9~N13 IPL与JOA评分呈显著负相关。N13潜伏期和N9~N20 IPL与JOA评分呈负相关。结论 N9~N13 IPL与CSM患者脊髓功能障碍程度显著相关,可作为CSM患者脊髓功能评估的电生理指标。

Correlation analysis between cortical somatosensory evoked potential and spinal cord function in patients with cervical spondylitic myelopathy

Objective To study the correlation between cortical somatosensory evoked potential(CSEP) and spinal cord function in patients with cervical spondylitic myelopathy(CSM). Methods From July 2008 to May 2012, N13 and N20 latency, N9-N20 and N9-N13 interpeak latency(IPL), P13-N13 and P20-N20 peak-peak amplitude(PPA) of 67 CSM patients were recorded through Endeavor CR monitor. Japanese Orthopaedic Association(JOA) scores of all the patients were recorded. The CSEP values and JOA scores were plotted as the scatter diagram. When the observed point distribution became a linear trend, the linear correlation analysis was performed. Results N9-N13 IPL was significantly negative linear correlation with JOA scores. N13 latency and N9-N20 IPL were negative linear correlation with JOA scores. N20 latency, P13-N13 and P20-N20 PPA were not linear correlation with JOA scores. Conclusion N9-N13 IPL is significantly negative linear correlation with CSM, So it can be an accurate and objective electrophysiological index for diagnosis and assessment of spinal cord function in patients with CSM.