大麻类物质与胃肠运动

大麻类物质在临床的应用已有多年,但迄今为止对大麻素系统的作用机制,尤其对内源性大麻素系统参与胃肠运动调节的机制并不明了.本文介绍大麻类物质的种类,其受体、同类物、拮抗剂以及它们对胃肠运动的影响等,以望为大麻素类物质在临床的应用提供理论基础及实验依据,并为进一步开展对大麻素系统的探讨与研究提供近期的资料和信息.

Cannabinoid system and its role in the intestinal motility regulation

Cannabinoids have been used in clinic for many years.However,their effective mechanisms,especially the role of the endogenous cannabinoid system in the regulation of intestinal motility are still poorly understood.In this article,we introduced that the compositions of the Cannabinoid family members,including their receptors,analogues,and antagonists,and the effects of them on the gastrointestinal movement.We provide the useful update information for the further clinic and experiment study on the cannabinoid family and the endocannabinoid system.