| 骨桥蛋白信号通路与肿瘤转移 |
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| 引用本文： | 陈荣新,叶胜龙.骨桥蛋白信号通路与肿瘤转移[J].国际外科学杂志,2007,34(9):626-628. |
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| 作者姓名： | 陈荣新 叶胜龙 |
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| 作者单位： | 上海复旦大学附属中山医院复旦大学肝癌研究所,200032 |
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| 摘 要： | 骨桥蛋白（osteopontin OPN）是一种具有多种功能的细胞外基质蛋白。OPN与其受体（整合素或CD44V）结合后激活细胞内多条信号通路,参与肿瘤转移的多个过程。本文综述OPN相关信号通路促进肿瘤转移的研究。
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| 关 键 词： | 骨桥蛋白 肿瘤 转移 |
| 修稿时间： | 2007-06-25 |
Osteopontin-related signal pathways and tumor metastasis |
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| CHEN Rong-Xin,YE Sheng-long.Osteopontin-related signal pathways and tumor metastasis[J].International Journal of Surgery,2007,34(9):626-628. |
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| Authors: | CHEN Rong-Xin YE Sheng-long |
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| Institution: | Zhongshan Hospital, Liver Cancer Institute, Fudan University, Shanghai 200032, China |
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| Abstract: | Osteopontin is a kind of multifunctional extracellular matrix protein.Osteopontin combining with its receptors(including integrins,CD44V)triggers many intracellular signal pathways to in paticipate many processes of tumor metastasis.The signal pathways induced by osteopontin in the tumor metastasis are discussed in this review. |
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| Keywords: | osteopontin tumor metastasis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
