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Immunomodulation in Transplantation with Photopheresis
Authors:Mark L Barr
Institution:the University of Southern California, Division of Cardiothoracic Surgery, Los Angeles, California, U.S.A.
Abstract:Abstract: Photopheresis is a technique in which peripheral blood mononuclear cells, in the presence of a photoacti-vatable compound, are exposed extracorporeally to ultraviolet A light and reinfused, inducing a host autoregula-tory immune response. Experimental work and ongoing clinical studies are helping to define the role of this novel, safe, and non-toxic immunomodulating technology in the field of transplantation.
Keywords:hotopheresis–  Photochemotherapy–  Immunomodulation–  Transplantation–  Immunosuppression
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