| 糖尿病肾病现状与挑战 |
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| 作者姓名： | 孙林 赵浩 |
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| 作者单位： | 1. 410011 长沙，中南大学肾脏病研究所，湘雅二医院肾内科 |
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| 基金项目： | 国家自然科学基金重点项目(81730018); 国家自然科学基金面上项目(81570622); 国家自然科学基金面上项目(81470960); 国家重大基础研发计划项目(2016YFC1305501) |
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| 摘 要： | 糖尿病肾病(DN)是糖尿病的严重并发症，近年来DN发病率呈不断上升趋势，是发达国家终末期肾病(ESRD)的主要病因，也是我国中老年人ESRD的主要病因。提高DN的认识与管理具有重大意义。本文对近年来国内外有关DN的流行病学、临床与病理诊断、易感基因、生物标志物及其治疗等方面的最新进展进行述评，同时对DN治疗现状与面临的挑战提出新的认识，以引起同行重视。
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| 关 键 词： | 糖尿病 糖尿病肾病 诊断 治疗 |
| 收稿时间： | 2018-11-19 |
The present status and challenges of diabetic nephropathy |
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| Authors: | Lin Sun Hao Zhao |
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| Institution: | 1. Department of Nephrology, Xiangya Second Hospital, Institute of Nephrology, Central South University, Changsha 410011, Hunan Province, China |
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| Abstract: | Diabetic nephropathy (DN) is a serious complication of diabetes mellitus. Recently, the incidence of DN has been on the rise, and it has become the main cause of end-stage renal disease (ESRD)in developed countries and also the main cause of ESRD in middle-aged and elderly people in China. It is of great importance to improve the understanding and management of DN. This article was aimed to review the new findings of epidemiology, clinical and pathological diagnosis, susceptibility genes, biomarkers, and treatment of DN in recent years, and gave some new understandings about the present treatment status and challenges of DN to attract the attention of the peers. |
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| Keywords: | Diabetes mellitus Diabetic nephropathy Diagnosis Treatment |
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