Chronic renal failure in Kuwaiti children: an eight-year experience |
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Authors: | Amal Al-Eisa Majeda Naseef Nadia Al-Hamad Raimundo Pinto Nofoud Al-Shimeri Mazen Tahmaz |
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Affiliation: | (1) Department of Pediatrics, Faculty of Medicine, Kuwait University, P.O. Box 24923, 13110 Safat, Kuwait;(2) Department of Pediatrics, Mubarak Hospital, Ministry of Health, Kuwait;(3) Department of Pediatrics, Adan Hospital, Ministry of Health, Kuwait;(4) Department of Pediatrics, Farwaniya Hospital, Ministry of Health, Kuwait;(5) Department of Pediatrics, Jahra Hospital, Ministry of Health, Kuwait |
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Abstract: | Over an 8-year period (January 1996 to December 2003), a total of 171 patients below the age of 15 years were diagnosed with chronic renal failure. The mean incidence rate of CRF in Kuwaiti children was found to be 38.2 per million children per year, with a peak incidence of 55 per million children per year. While the mean age at diagnosis was 33±12 months (range: 1 month to 15 years), the male:female ratio was 2.7:1. Etiological factors for chronic renal failure included congenital urological malformation (61.9%), chronic glomerulopathies (5.2%), hereditary nephropathies (21%), multi-system disease (0.5%), chronic pyelonephritis (without VUR) (4.6%), tumors (0.6%), ischemic renal disease (1.1%) and unknown etiology (1.7%). Thirty percent of patients reached end-stage renal disease within a mean of 18 months following diagnosis. The overall mortality before reaching ESRD was reported to be 4%. Kuwait has one of the highest incidence and prevalence rates of CRF in children. It is likely that genetic and hereditary factors are the cause of these high rates. |
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Keywords: | Chronic renal failure (CRF) Dialysis Uropathy Posterior urethral valve (PUV) Glomerulopathy Vesicoureteric reflux (VUR) |
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