虚拟中国人女性一号肝脏图像三维重建和虚拟手术的切割

目的研究数字化虚拟肝脏三维重建及虚拟肝脏手术的切割。方法采用数字化虚拟中国人女性一号(Virtual Chinese Human Female No．1 VCH-F1)数据集中所有包含肝脏的连续图像,首先对组织切片图像进行配准后从中分割提取出肝实质、肝静脉、胆管、胆囊等组织的图像信息,然后应用可视化工具包(Visualization Toolkit,VTK)三维重建,建立肝脏表面及内部结构的三维形态模型,并开发一个基于PC机和Windows平台的肝脏三维可视化演示系统。结果在肝脏三维可视化演示系统中,肝脏实体立体感强,可以通过设定肝脏及其管道系统的透明度,以及对模型的放大、缩小和上下左右不同方向的旋转,来观察肝脏及管道结构的立体形态。并可以按任意角度对虚拟的肝脏进行切割和观察切割面结构。结论利用VCH-F1数据集中肝脏图像,在VTK基础上开发的基于PC机和Windows平台的肝脏三维可视化演示系统基本达到了比较满意的程度,为今后数字化虚拟肝脏及虚拟各种肝脏手术的研究做了积极探索。

Studies on the hepatic three-dimensional reconstruction and virtual surgery using the hepatic images of the digitized virtual Chinese human female number 1 database

Objective To study digitized virtual hepatic three-dimesional reconstruction and virtual hepatic surgery. Methods The whole series of hepatic images taken from the database of digitized Virtual Chinese Human Female Number 1 (VCH-F1) was employed to reconstruct a three-dimensional (3D) liver. First, studied some algorithms for registration of human liver tissue images, and then, segmented the regions of liver, vein, bile duct, and gallbladder from the images. Based on them, the 3D visualization human liver model was reconstructed. Finally, a 3D visualization demo system of liver was developed based on personal computer and Windows operation system. Results This demo system of liver provided a graphics user interface to rotate, scale the 3D liver to observe the 3D hepatic structure, and a virtual liver simulation system of resection with primary function. Conclusions The study may be beneficial to the future research on digitized virtual hepatic and virtual hepatic surgery, and the 3D visualization demo system of liver may be beneficial to the research on the hepatic structure.