Clinicopathologic and Technical Factors Associated with the Uptake of Radiocolloid by Sentinel Nodes in Patients with Breast Cancer |
| |
Authors: | Kazuhiko Sato Kuniyoshi Tamaki Takashi Shigekawa Hitoshi Tsuda Shigeru Kosuda Shoichi Kusano Hoshio Hiraide Hidetaka Mochizuki |
| |
Institution: | (1) Department of Surgery I, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan, JP;(2) Department of Pathology II, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan, JP;(3) Department of Radiology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan, JP;(4) Research Institute, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan, JP |
| |
Abstract: | Purpose. Sentinel-node biopsy is becoming widely accepted in breast cancer treatment. Using the radioisotope technique, a lower risk
of identification failure is related to the amount of radiocolloid in the sentinel nodes. The aim of this study was to identify
the factors associated with the colloidal uptake of the sentinel nodes.
Methods. Technetium-labeled colloid was injected peritumorally, with or without subdermal injection. According to the maximum radioactivity
of the sentinel nodes, patients were divided into high (≥100 counts/s) or low (<100 counts/s) uptake groups. The uptake was
compared in relation to the clinicopathologic and technical features.
Results. The sentinel node was identified in 183 of 186 patients (98.4%), with 60 and 123 patients in the low- and high-uptake groups
(mean: 39 and 1003 counts/s), respectively. Multivariate analysis showed that an age of 65 years or older and a sentinel-node
size of 8 mm or more were significantly more predominant in the low-uptake group.
Conclusion. Care must be taken when performing sentinel-node biopsy, especially for aged patients and for those with large sentinel nodes.
The optimal technique should be determined on the basis of these results.
Received: March 29, 2002 / Accepted: November 19, 2002
RID="*"
ID="*" Reprint requests to: K. Sato |
| |
Keywords: | Sentinel node Breast cancer Radioisotope technique Uptake of radiocolloid |
本文献已被 PubMed SpringerLink 等数据库收录! |
|