HBV感染肝癌患者血清HBV DNA水平与手术近期疗效的关系

目的 探讨血清HBVDNA水平与HBV感染原发性肝癌手术治疗近期疗效的关系.方法 100例HBsAg 阳性手术切除的原发性肝癌病例,检测术前、术后1周血清HBVDNA,与各项临床指标,术后血ALT、TB峰值及肝功能恢复时间行统计学分析.结果 本组病例术前HBVDNA阳性率达79%,肝切除前后血清HBVDNA水平变化无显著性差异(配对t检验P=0.204);术前血清HBVDNA水平与肝癌切除后血清ALT峰值及肝功能恢复时间呈显著性正相关(P

THE RELATIONSHIP BETWEEN THE LEVEL OF HBV DNA IN SERUM AND THE RECENTLYOPERATIVE EFFECT OF PRIMARY HEPATOCARCINOMA WITH HBV INFECTION

Objective Investigate The relationship between the level of HBV DNA in serum and the recently operative effect of PHC.Methods The preoperative and one week post preoperative serum HBV DNA level were measured by PCR in 100 PHC patients with HBsAg positive.the clinical features and the change of postoperative liver function were analized by SPSS software.Results 1.The positive rate of serum HBV DNA in all cases of PHC was 79%.2.The serum HBVDNA level in preoperation was not significantly different with that in postoperation.(Paried-samples T-test P=0.204) 3.The preoperative serum HBV DNA level was significantly positive correlated with the peak value of serum HBV DNA level and the recovery period of liver function after hepatectomy.Conclusions The most of PHC patients with HBV infection were in the active phase of HBV infection;the serum HBV DNA level was not influenced by the hepatectomy;but the high level of serum HBV DNA would result in the aggravation of hepatic dysfunction and the extend of liver function recovery.