完整结肠系膜切除治疗结肠癌的疗效分析

目的：评价完整结肠全系膜切除（CME）治疗结肠癌的临床疗效。 方法：选取结肠癌患者62例，随机均分为两组，分别采用CME手术（CME组）和传统根治术（传统组），对比两组的相关临床指标。 结果：与传统组比较，CME组术中出血量明显减少（P<0.05）；手术时间、排气时间、排便时间组间差异均无统计学意义（均P>0.05）；两组近切端、远切端长度差异无统计学意义（均P>0.05）；CME组III期患者淋巴结清扫数目多于传统组（P<0.05），但两组III期阳性淋巴结数差异未达统计学意义（P>0.05）；两组并发症发生率差异无统计学意义（P>0.05）；CME组复发率低于传统组（6.45 vs. 22.58，P<0.05）。 结论：CME根治术能增加清扫淋巴结的数量且不增加并发症的发生率，有利于改善结肠癌患者预后。

Efficacy of complete mesocolic excision in treatment of colon cancer

Objective: To assess the clinical efficacy of complete mesocolic excision (CME) in treatment of colon cancer. Methods: Sixty-two patients with colon cancer were equally designated to two groups, and underwent CME radical resection (CME group) and traditional radical resection (traditional group), respectively. The relevant clinical variable between the two groups were compared. Results: In CME group compared with traditional group, the intraoperative blood loss was significantly reduced (P<0.05), but the differences in operative time, and time to flatus and defecation had no statistical significance (all P>0.05). The distance of either the proximal or distal surgical margin from the tumor showed no statistical difference between the two groups (both P>0.05). The number of resected lymph nodes in stage-III patients in CME group was significantly greater than that in traditional group (P<0.05), but number of positive lymph nodes in stage-III patients did not reach a statistical difference between the two groups (P>0.05). No statistical difference was noted in incidence of complications between the two groups (P>0.05), but the recurrence rate in CME group was significantly lower than that in traditional group (6.45 vs. 22.58, P<0.05). Conclusion: CME radical resection can increase the number of lymph nodes resected without risk of increased complications, and thereby may help improve the prognosis of colon cancer patients.