巨块型肝癌合并门静脉癌栓的治疗：附15例报告

目的　探讨外科手术、肝动脉化疗栓塞及联合或不联合门静脉灌注化疗治疗巨块型肝癌伴门静脉癌栓的效果。方法　 15例伴有门静脉癌栓的巨块型肝癌 ,均采用切除原发癌灶并取尽癌栓治疗 ,其中 5例患者留置门静脉化疗泵 ,术后 2周行肝动脉化疗栓塞或联合门静脉化疗。结果　全组术后无严重并发症发生。 6,12 ,18个月生存期分别为 10 0 % (15 /15 ) ,80 .0 % (12 /15 ) ,60 .0 %(9/15 )。结论　手术仍是治疗巨块型肝癌合并门静脉癌栓的有效方法 ,手术后辅以介入为主的综合治疗能有效提高生存率。

Treatment of hepatocellular carcinoma with tumor thrombus of the portal vein:a report of 15 cases

Objective To evaluate the effect of combination of surgery and transcatheter hepatic arterial chemotherapic embolism(THACE) with or without placement of drug deliery system(DDS) of portal vein for hepatocellular carcinoma with portal vein tumor thrombus (PVTT). Methods Fifteen cases of advanced HCC with PVTT were treated by hepatectomy, thrombectomy of portal vein with THACE,and 5 of the 15 cases received postoperative chemotherapy via portal vein. Results All patients survived after operation. The survival rate of 6,12,18 months was 15,12 and 9 cases respectively. Conclusions Operation is still an effective method for advanced HCC , postoperative comprehensive treatment can improve the survival rate.