Prospective Randomized Trial Comparing Billroth I and Roux-en-Y Procedures after Distal Gastrectomy for Gastric Carcinoma |
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Authors: | Makoto Ishikawa MD Joji Kitayama MD PhD Shoichi Kaizaki MD Hiroshi Nakayama MD PhD Hironori Ishigami MD Shin Fujii MD PhD Hiroyuki Suzuki MD Tomomi Inoue MD PhD Akihiro Sako MD PhD Masahiro Asakage MD Hiroharu Yamashita MD Kenji Hatono MD PhD Hirokazu Nagawa MD PhD |
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Institution: | (1) Department of Surgery, Division of Surgical Oncology, The University of Tokyo, 7-3-1 Hongo, Bankyo-ku Tokyo, 113-8655, Japan |
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Abstract: | To determine the clinical efficacy of Roux-en-Y reconstruction (RY) after distal gastrectomy, we compared postoperative outcomes
of patients who underwent RY or conventional Billroth I reconstruction (B-I). A total of 50 patients were prospectively randomized
to either B-I or RY reconstruction, and complications, postoperative course, and nutritional status were compared. Bile reflux
and inflammation in the remnant stomach and lower esophagus were evaluated by postoperative follow-up endoscopy at 6 months.
Operative time and blood loss as well as postoperative nutrition did not show significant differences between the two groups.
As anticipated, 5 of 24 patients with RY reconstruction developed gastrojejunal stasis in the early postoperative period,
which led to a longer postoperative hospital stay as compared with the B-I group (mean ± S.D; B-I; 19.0 ± 6.2, RY; 31.8 ±
21.7 days) (P < 0.05). Endoscopic examination revealed that the frequency of bile reflux (P < 0.01) and degree of inflammation in the remnant stomach (P < 0.05) were less in the RY group than in the B-I group. However, inflammatory findings in the lower esophagus were observed
in 7 (27%) of B-I, and 8 (35%) of the RY group, suggesting that late phase esophagitis was not improved in the RY group. Roux-en-Y
reconstruction was effective in preventing duodenogastric reflux and resulting gastritis, but it did not prevent esophagitis.
Because RY reconstruction induces the frequent complication of Roux-en-Y stasis, causing longer postoperative hospital stay,
this method has limited advantages over B-I anastomosis after distal gastrectomy. |
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