心脏外科手术后急性肾功能衰竭的防治进展

急性肾功能衰竭（acute renal failure，ARF）是心脏手术后的严重并发症之一，是增加手术死亡率，延长机械通气时间和重症监护室停留时间，导致认知功能障碍、呼吸功能衰竭等主要脏器并发症，增加住院费用等的重要影响因素。研究表明体外循环和主动脉球囊反搏（IABP）的使用，术前肾功能不全、糖尿病以及外周血管疾病是术后ARF的风险因素，经过容量血管收缩、肾脏灌注不足、缺血一再灌注损伤等病理生理改变，导致ARF的发生。适当使用药物治疗、血液透析、血液滤过可以保护肾功能，改善ARF的预后。

Prevention and Treatment of Acute Renal Failure after Cardiac Surgery

Acute renal failure(ARF)is a serious complication after cardiac surgery.It is an important influential factor of increasing mortality,extending mechanical ventilation time and intensive care unit time,resulting in cognition functional impairment and respiratory function failure et al,and increasing cost of hospitalization.Extracorporeal circulation,intra-aortic balloon pump,renal inadequacy before surgery,diabetes and peripheral vascular disease are all risk factors of ARF after operation.These factors can ...