七叶皂苷片促进合并组织学炎症的前列腺增生患者术后下尿路症状的改善

目的探讨将七叶皂苷片应用于合并前列腺组织学炎症的前列腺增生（BPH）患者，观察其对经尿道前列腺电切术（TURP）后早期下尿路症状（LUTS）的改善作用。 方法2015年11月至2018年5月，我院116例合并前列腺组织学炎症的BPH患者，随机分为治疗组（n=58）和对照组（n=58），均行TURP。治疗组在对照组基础上，从手术后第3天起开始口服七叶皂苷片2片/次，2次/d，直至拔导尿管后4周。记录两组患者术前、拔管后第7天和拔管后第28天的国际前列腺症状评分（IPSS）和生活质量（QOL）评分，并记录两组急性尿潴留（AUR）和急迫性尿失禁（UUI）发生的例数。 结果两组患者术后IPSS和QOL评分均较术前有明显下降，但治疗组较对照组的IPSS和QOL评分下降幅度更大，差异有统计学意义（P<0.05），治疗组发生UUI的例数明显少于对照组，差异有统计学意义（P<0.05），而两组发生AUR的例数差异无统计学意义。 结论七叶皂苷片可以促进合并前列腺组织学炎症的BPH患者TURP术后早期LUTS的改善。

The study of Aescuven forte in improving lower urinary tract symptoms in benign prostatic hyperplasia patients with histological prostatitis after transurethral resection of the prostate

ObjectiveTo evaluate the therapeutic efficacy of Aescuven forte on lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH) patients with histological prostatitis after transurethral resection of prostate (TURP). MethodsFrom November 2015 to May 2018, 116 BPH patients with histological prostatitis were randomized divided into two groups with 58 cases in the treatment group and 58 cases in the control group. The treatment group received aescuven forte 2 pieces bid started at 3 days after surgery and continued till 4 weeks after catheter removal, while the control group received no such treatment. The IPSS and QOL scores were observed before surgery and at 7 days, 28 days after catheter removal. The numbers of AUR and UUI after surgery were counted. ResultsThe IPSS and QOL scores after surgery were significantly lower than the those before surgery in both groups. But there were significant difference in the declining range between the two groups (P<0.05). The incidence of UUI was much lower in the treatment group than that in the control group (P<0.05), while the incidence of AUR in two groups showed no statistical difference (P>0.05). ConclusionAescuven forte can improve the LUTS after TURP in BPH patients with histological prostatitis.