口腔卫生与慢性胃炎关系的临床研究

目的 :为探讨口腔卫生与慢性胃炎的关系。方法 :76例胃粘膜幽门螺杆菌 (Helicobacterpylori,Hp)检测阳性慢性胃炎患者为慢性胃炎组 ,72例健康自愿者组成对照组 ,对所有受检者进行口腔卫生检查 ,并对其牙菌斑Hp进行检测 ,比较两组的差别 ;慢性胃炎组随机分成A、B两组后接受抗Hp治疗 ,A组同时进行口腔治疗与口腔教育 ,B组为对照 ,3月后观察抗Hp治疗的疗效 ,比较两组的差别。 结果 :慢性胃炎组口腔卫生状况明显较对照组差 (P<0 .0 1) ,且口腔卫生状况与慢性胃炎程度有关 (P <0 .0 5 ) ;牙菌斑Hp检测结果亦显示口腔卫生愈差、慢性胃炎愈严重 ,Hp阳性率愈高。 3月后A组的疗效明显优于B组。 结论 :口腔卫生好坏与慢性胃炎的发病密切相关 ,Hp寄生于牙菌斑可能是导致慢性胃炎发病和复发的一个重要因素。

A clinical study on the relationship between oral hygiene and chronic gastritis.

Objective:To investigate the relationship between oral hygiene and chronic gastritis.Methods:76 patients with chronic gastritis (Helicobacter pylori polymerase chain reaction detection were positive, Hp-PCR positive) and 72 controls were studied their oral hygiene and the Hp in their dental plaque.Chronic gastritis patients were received anti-Hp therapy and then divided into 2(A and B)groups.A group was treated by supergingival subgingival curettage,and received oral health education while B group was compared.Results:There were significant differences of Hp positive rate and debris index(DI),calculus index(CI),plaque index(PLI),gingival index(GI) between chronic gastritis group and control group( P< 0.01),and they all related with the severity of chronic gastritis( P <0.01).Oral hygiene treatment and oral health education are benefit for anti-Hp therapy of chronic gastritis.Concusions:It is indicated that the relationship between oral hygiene and chronic gastritis is close clinically,Hp in dental plaque perhaps is one of the way to Hp infecton.