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从细胞到器官--牙组织工程任重而道远
引用本文:胡冰,刘怡,王松灵.从细胞到器官--牙组织工程任重而道远[J].上海口腔医学,2005,14(2):99-102.
作者姓名:胡冰  刘怡  王松灵
作者单位:首都医科大学口腔医学院,基因治疗分子生物学实验室,北京,100050;首都医科大学口腔医学院,基因治疗分子生物学实验室,北京,100050;首都医科大学口腔医学院,基因治疗分子生物学实验室,北京,100050
摘    要:Tooth tissue engineering is an emerging biotechnique that will provide replacemental teeth for patients suffering from different diseases causing tooth loss. Although some attempts have been tried to generate whole tooth both in vivo and in vitro, the lack of the knowledge for tooth initiation and development, as well as for tooth shape controlling mechanisms greatly impede the progress of this technique. This article reviewed and discussed some recent findings in tooth tissue engineering related to the cell resource, the concept of reconstruction and regeneration, the application of artificial scaffolds, together with the methods of organ culture and implantation.

关 键 词:细胞  器官  牙组织工程  牙发生发育  生物支架
文章编号:1006-7248(2005)02-0099-04
修稿时间:2005年4月7日

Tooth tissue engineering: from cells to organ, an odyssey far from finished
HU Bing,LIU Yi,WANG Song-ling.Tooth tissue engineering: from cells to organ, an odyssey far from finished[J].Shanghai Journal of Stomatology,2005,14(2):99-102.
Authors:HU Bing  LIU Yi  WANG Song-ling
Abstract:Tooth tissue engineering is an emerging biotechnique that will provide replacemental teeth for patients suffering from different diseases causing tooth loss. Although some attempts have been tried to generate whole tooth both in vivo and in vitro, the lack of the knowledge for tooth initiation and development, as well as for tooth shape controlling mechanisms greatly impede the progress of this technique. This article reviewed and discussed some recent findings in tooth tissue engineering related to the cell resource, the concept of reconstruction and regeneration, the application of artificial scaffolds, together with the methods of organ culture and implantation.
Keywords:Tooth  Tissue engineering  Bioengineered teeth  Developmental biology
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