渐进性负荷对即刻植入种植体早期骨性结合的影响

目的 观察渐进性负荷后即刻植入种植体骨结合的早期X线及扫描电镜改变。方法 选取4只健康雄性Beagle犬，于手术当天、术后第14天和第21天在麻醉下分别拔除双侧下颌第三前磨牙、第二前磨牙、第四前磨牙后即刻种植，共植入24颗种植体。术后24 h开始给予一侧下颌骨内种植体渐进性功能负荷，另一侧不给予负荷。分别于手术当天及术后第7、14、21、28天拍摄X线片，测量垂直骨吸收量（VBL）。实验第28天取材，进行扫描电镜观测。结果 对照组VBL明显大于渐进性负荷组，二者比较有统计学意义（P＜0.05）。扫描电镜观察渐进性负荷组种植体表面骨形成速度明显快于对照组。结论 即刻种植后给予渐进性垂直负荷不干扰种植体骨性结合过程，且可能有协同拔牙创的愈合作用，从而促进种植体骨性结合。

Effects of Progressive Loading on Implants Placed into Extraction Sockets: A Preliminary Study

Objective To study the effects of progressive loading on implants placed into extraction sockets.Methods Bilateral 3rd,4th and 2nd premolar of 4 beagle dogs were extracted and the implants were immediately inserted at 0,14 and 21 days.The progressive loading procedure was conducted after 24 hours.The vertical bone loss(VBL) and the bone/biomaterials reactions were detected by X-ray and SEM.Results The VBL in control groups was larger than that for the experimental groups at 14,21 and 28 days(P<0.05).Scan electron microscopy detected that the mineralization speed of experimental groups was many times as faster as the control groups.Conclusion Progressive loading of implants placed into extraction sockets can be performed without disturbing the osseointegration process.The potential of new bone formation in the extraction sockets and the physical strains can congenerously promote osseointegration.