首页 | 本学科首页   官方微博 | 高级检索  
按 检索        


Healing of experimental gingival recession defects treated with amnion allograft: Histologic and histometric analysis in dogs
Institution:1. Department of Oral Medicine, Periodontology, Oral Diagnosis and Oral Radiology, Faculty of Dentistry, Tanta University, Tanta, Egypt;2. Department of Surgery, Anesthesia, and Radiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt;1. Developmental Biology of Hard Tissue, Graduate School of Dental Medicine, Faculty of Dental Medicine, Hokkaido University, Sapporo, Japan;2. Oral and Maxillofacial Surgery, Graduate School of Dental Medicine, Faculty of Dental Medicine, Hokkaido University, Sapporo, Japan;3. Biomaterials and Bioengineering, Graduate School of Dental Medicine, Faculty of Dental Medicine, Hokkaido University, Sapporo, Japan;4. Orthodontics, Graduate School of Dental Medicine, Faculty of Dental Medicine, Hokkaido University, Sapporo, Japan;5. Northern Army Medical Unit, Camp Makomanai, Japan Ground Self-Defense Forces, Sapporo, Japan;6. Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan;7. Central Research Institute, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan;8. Shandong Provincial Key Laboratory of Oral Biomedicine, The School of Stomatology, Shandong University, Jinan, China;1. Division of Forensic Odontology, Department of Diagnostic ＆ Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan;2. Division of Dental Radiology, Department of Diagnostic ＆ Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan;3. Forensic Odontology Center, Meikai University School of Dentistry, Saitama, Japan;4. Department of Legal Medicine, Nihon University School of Dentistry, Tokyo, Japan;1. Oral Biology and Biochemistry Research Group, Unidade de Investigação Em Ciências Orais e Biomédicas (UICOB), Faculdade de Medicina Dentária, Universidade de Lisboa, Lisboa, Portugal;2. Center for Microelectromechanical Systems (CMEMS), Dept. of Mechanical Engineering, University of Minho, Guimarães, Portugal;3. Oral Biology and Biochemistry Research Group, Unidade de Investigação Em Ciências Orais e Biomédicas (UICOB), LIBPhys-FCT UID/FIS/04559/2013, Faculdade de Medicina Dentária, Universidade de Lisboa, Lisboa, Portugal;4. CEMDBE - Cochrane Portugal, Faculdade de Medicina Dentária, Universidade de Lisboa, Lisboa, Portugal;5. Implant & Tissue Regeneration Group, Unidade de Investigação Em Ciências Orais e Biomédicas (UICOB), LIBPhys-FCT UID/FIS/04559/2013, Universidade de Lisboa, Faculdade de Medicina Dentária, Lisboa, Portugal;1. Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA;2. Department of Oral Physiology, Asahi University School of Dentistry, 1851-1 Hozumi, Mizuho, Gifu 501-0296, Japan;3. Obesity Institute, Geisinger Medical Center, 100 North Academy Ave, Danville, PA 17822, USA;4. Graduate School of Dental Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582 Japan;5. Oral Health Science Center, Tokyo Dental College, 2-9-18 Kandamisaki-cho, Chiyoda-ku, Tokyo 101-0061 Japan;6. Department of Oral Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1, Shikata-cho, Kita-ku, Okayama, 700-8558 Japan
Abstract:ObjectivesThis study was conducted to compare the healing response of localized gingival recession defects treated with a coronally advanced flap (CAF) and either an amnion allograft membrane (AM) or a connective tissue graft (CTG).MethodsGingival recession defects were surgically created in six healthy mongrel dogs at the labial root surface of the maxillary canines, bilaterally. Using a split mouth design, the defects were treated with CAF and either AM (CAF/AM) or CTG (CAF/CTG). Three animals for each group were scarified at 1 and 3 months. Segments containing the defects were prepared for histological and histometric analysis.ResultsBoth techniques showed similar clinical findings with adequate root coverage. Histologically, healing was characterized by the formation of new cementum and new connective tissue attachment in the CAF/AM group; in the CAF/CTG group, healing was characterized by junctional epithelium, coronally, and connective tissue fibers parallel to the root surface, apically. Histometrically, the CAF/AM group revealed a substantially shorter epithelial length and a longer, new cementum compared with those of the CAF/CTG group after a healing period of 3 months.ConclusionsWithin the limits of this study, we concluded that the AM allograft could promote periodontal healing in gingival recession defects.
Keywords:Gingival recession  Connective tissue  Amnion  Guided tissue regeneration  Dogs  AM"}  {"#name":"keyword"  "$":{"id":"kwrd0040"}  "$$":[{"#name":"text"  "_":"amnion allograft membrane  CAF"}  {"#name":"keyword"  "$":{"id":"kwrd0050"}  "$$":[{"#name":"text"  "_":"coronally advanced flap  CTG"}  {"#name":"keyword"  "$":{"id":"kwrd0060"}  "$$":[{"#name":"text"  "_":"connective tissue graft  CEJ"}  {"#name":"keyword"  "$":{"id":"kwrd0070"}  "$$":[{"#name":"text"  "_":"cemento-enamel junction  ADM"}  {"#name":"keyword"  "$":{"id":"kwrd0080"}  "$$":[{"#name":"text"  "_":"acellular dermal matrix  EMD"}  {"#name":"keyword"  "$":{"id":"kwrd0090"}  "$$":[{"#name":"text"  "_":"enamel matrix derivative  GTR"}  {"#name":"keyword"  "$":{"id":"kwrd0100"}  "$$":[{"#name":"text"  "_":"guided tissue regeneration  MGJ"}  {"#name":"keyword"  "$":{"id":"kwrd0110"}  "$$":[{"#name":"text"  "_":"mucogingival junction  H&E"}  {"#name":"keyword"  "$":{"id":"kwrd0120"}  "$$":[{"#name":"text"  "_":"hematoxylin and eosin  EGF"}  {"#name":"keyword"  "$":{"id":"kwrd0130"}  "$$":[{"#name":"text"  "_":"epidermal growth factor  FGF"}  {"#name":"keyword"  "$":{"id":"kwrd0140"}  "$$":[{"#name":"text"  "_":"fibroblast growth factor  PDGF"}  {"#name":"keyword"  "$":{"id":"kwrd0150"}  "$$":[{"#name":"text"  "_":"platelet derived growth factor  VEGF"}  {"#name":"keyword"  "$":{"id":"kwrd0160"}  "$$":[{"#name":"text"  "_":"vascular endothelial growth factor  PDL"}  {"#name":"keyword"  "$":{"id":"kwrd0170"}  "$$":[{"#name":"text"  "_":"periodontal ligament
本文献已被 ScienceDirect 等数据库收录！
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号